Simple automated system for simultaneous production of 11C-labeled tracers by solid supported methylation
Keywords: 
Simultaneous synthesis
[11C]methylation
[11C]methionine
[11C]choline
Issue Date: 
15-Feb-2006
Publisher: 
Elsevier
ISSN: 
0969-8043
Citation: 
Quincoces, G. (Gemma); Peñuelas, I. (Iván); Valero, M. (Marta); et al. "Simple automated system for simultaneous production of 11C-labeled tracers by solid supported methylation". En . , 2006-02-15,
Abstract
We herein describe a simple setup for the automated simultaneous synthesis of l-[methyl-11C]methionine and N-[methyl-11C]choline by solid-supported methylation . The setup is extremely simple and easy to adapt to other automated systems and due to its versatility, the method can be utilized for the production of other radiopharmaceuticals requiring a simple [11C]methylation step. Furthermore, it can be used for multiple simultaneous synthesis.

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