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Dadun > Depósito Académico > CIMA (Centro de Investigación Médica Aplicada) > Área de Oncología > Terapia celular > DA - CIMA - Oncología - Terapia celular - Artículos de Revista >

Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: updated time-to-events results and prognostic factors for time to progression
Authors: Mateos, M.V. (María Victoria)
Hernandez, J.M. (J. M.)
Hernandez, M.T. (M. T.)
Gutierrez, N.C. (N. C.)
Palomera, L. (Luis)
Fuertes, M. (M.)
Garcia-Sanchez, P. (P.)
Lahuerta, J.J. (Juan J.)
Rubia, J. (J.) de la
Terol, M.J. (María José)
Sureda, A. (Anna)
Bargay, J. (J.)
Ribas, P. (Paz)
Alegre, A. (A.)
Arriba, F. (F.) de
Oriol, A. (Albert)
Carrera, D. (D,)
Garcia-Laraña, J. (J.)
Garcia-Sanz, R. (R.)
Blade, J. (J.)
Prosper, F. (Felipe)
Mateo, G. (Gemma)
Esseltine, D.L. (D. L.)
Velde, H. (Helgi) van de
San-Miguel, J.F. (Jesús F.)
Keywords: Materias Investigacion::Ciencias de la Salud::Oncología
Issue Date: 2008
Publisher: Fondazione Ferrata Storti
Publisher version:
ISSN: 0390-6078
Citation: Mateos, M.-V., Hernández. J. M., Hernández, M. T., Gutiérrez, N. C. et al Haematologica 2008; 93(4): 560-565
New treatment options offering enhanced activity in elderly, newly diagnosed patients with multiple myeloma are required. One strategy is to combine melphalan and prednisone with novel agents. We previously reported an 89% response rate, including 32% complete responses and 11% near complete responses, in our phase 1/2 study of bortezomib plus melphalan and prednisone (VMP) in 60 newly diagnosed multiple myeloma patients with a median age of 75 years. Here, we report updated time-to-events data and the impact of poor prognosis factors on outcome.
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Appears in Collections:DA - CIMA - Oncología - Síndromes mieloproliferativos - Artículos de Revista
DA - CIMA - Oncología - Terapia celular - Artículos de Revista
DA - CUN - Área de Terapia Celular - Artículos de revista
DA - Medicina - Hematología - Artículos de revista

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