Epigenetic Signatures Associated with Different Levels of Differentiation Potential in Human Stem Cells

Prosper-Cardoso, F. (Felipe); Esteller, M. (Manel); Siebert, R. (Reiner); Cigudosa, J.C. (Juan Cruz); Martin-Subero, J.I. (Jose Ignacio); Prieto, I. (Inés); Roman-Gomez, J. (José); Andreu, E.J. (Enrique José); Ballestar, E. (E.); Aguirre-Ena, X. (Xabier); Aranda, P. (P.)

Keywords:

Materias Investigacion::Ciencias de la Salud::Oncología

Issue Date:

2009

Publisher:

Public Library of Science

Project:

222995 - INFARCT CELL THERAPY - Therapy after heart infarct: prevention of reperfusion injury and repair by stem cell transfer

ISSN:

1932-6203

Citation:

Aranda, P., Agirre, X., Ballestar, E., Andreu, E. J. et al. Epigenetic signatures associated with different levels of differentiation potential in human stem cells. PLoS ONE 2009; 4 (11)

Abstract

The therapeutic use of multipotent stem cells depends on their differentiation potential, which has been shown to be variable for different populations. These differences are likely to be the result of key changes in their epigenetic profiles.

URI:

https://hdl.handle.net/10171/17939

DOI:

http://dx.doi.org/10.1371/journal.pone.0007809

Appears in Collections:

DA - CIMA - Hemato-oncología - Síndromes mieloproliferativos - Artículos de Revista
DA - CIMA - Medicina regenerativa - Terapia celular - Artículos de Revista
DA - CUN - Área de Terapia Celular - Artículos de revista

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