Full metadata record
DC Field | Value | Language |
---|---|---|
dc.creator | Izal-Azcarate, A. (A.) | - |
dc.creator | Gutierrez-Perez, M. (María) | - |
dc.creator | Izal-Azcárate, I. (Íñigo) | - |
dc.creator | Belzunegui, S. (S.) | - |
dc.creator | San-Sebastian, W. (Waldy) | - |
dc.creator | Lopez, B. (Berta) | - |
dc.creator | Marcilla, I. (Irene) | - |
dc.creator | Prosper-Cardoso, F. (Felipe) | - |
dc.creator | Luquin, M.R. (María Rosario) | - |
dc.date.accessioned | 2011-05-19T12:38:13Z | - |
dc.date.available | 2011-05-19T12:38:13Z | - |
dc.date.issued | 2009 | - |
dc.identifier.citation | Izal-Azcarate, A., Gutierrez-Perez, M., Izal, I., Belzunegui, S. et al.Isolation, culture and characterization of adult carotid body-derived cells. Respiratory Physiology & Neurobiology (2009); 167: 201–207 | es_ES |
dc.identifier.issn | 1569-9048 | - |
dc.identifier.uri | https://hdl.handle.net/10171/18024 | - |
dc.description.abstract | Recent studies indicate that carotid body (CB) could be a suitable cell source for cell therapy in Parkinson’s disease.We have isolated and successfully expanded in culture as monolayer adult CB-derived cells using a modification of the culture medium employed for bone marrow multipotent adult progenitor cells (MAPCs). These cells express variable amounts of tyrosine hydroxylase (TH), -III tubulin and Sox2. In addition, CB-derived cells showed high expression of Sox2 related to a high rate of proliferation and consistent with an undifferentiated state. Under culture conditions that reduced cell proliferation, Sox2 expression decreased while TH and -III tubulin expression was increased. This could indicate that the differentiation of some cells occurs in the culture, thus accounting for a certain neural differentiation potential of CB-derived cells. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | info:eu-repo/semantics/closedAccess | - |
dc.subject | Carotid body cells | es_ES |
dc.subject | Cell theraphy | es_ES |
dc.subject | Parkinson disease | es_ES |
dc.title | Isolation, culture and characterization of adult carotid body-derived cells | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.identifier.doi | http://dx.doi.org/10.1016/j.resp.2009.04.021 | es_ES |
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