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Cellular Cardiomyoplasty: Clinical Application
Authors: Chachques, J. (J.)
Acar, C. (Christophe)
Herreros, J. (Jesús)
Trainini, J. (Jorge)
Prosper, F. (Felipe)
D’Attellis, N. (N.)
Fabiani, J.N. (J.N.)
Carpentier, A. (A.)
Keywords: Materias Investigacion::Ciencias de la Salud::Oncología
Issue Date: 2004
Publisher: Elsevier
Publisher version:
ISSN: 0003-4975
Citation: Chachques, J.C., Acar, C., Herreros, J., Trainini, J.C., Prosper, F., D’Attellis, N. et al. Cellular Cardiomyoplasty: Clinical Application. Ann. Thorac. Surg. 2004;77:1121–30
Myocardial regeneration can be induced with the implantation of a variety of myogenic and angiogenic cell types. More than 150 patients have been treated with cellular cardiomyoplasty worldwide, 18 patients have been treated by our group. Cellular cardiomyoplasty seems to reduce the size and fibrosis of infarct scars, limit postischemic remodelling, and restore regional myocardial contractility. Techniques for skeletal myoblasts culture and ex vivo expansion using autologous patient serum (obtained from plasmapheresis) have been developed by our group. In this article we propose (1) a total autologous cell culture technique and procedures for cell delivery and (2) a clinical trial with appropriate endpoints structured to determine the efficacy of cellular cardiomyoplasty.
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Appears in Collections:DA - CIMA - Oncología - Síndromes mieloproliferativos - Artículos de Revista
DA - CIMA - Oncología - Terapia celular - Artículos de Revista
DA - CUN - Área de Terapia Celular - Artículos de revista
DA - Medicina - Hematología - Artículos de revista

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