<td class= Dadun
   (New user)
Help  | Contact  |  Castellano English  

Dadun > Depósito Académico > Facultad de Farmacia > Departamento de Ciencias de la Alimentación, Fisiología y Toxicología > DA - Farmacia - CAFT - Artículos de revista >

Natural inhibitors of pancreatic lipase as new players in obesity treatment.
Authors: Garza, A.L. (Ana Laura) de la
Milagro, F.I. (Fermin Ignacio)
Boque, N. (Noemi)
Campion, J. (Javier)
Martinez, J.A. (José Alfredo)
Keywords: Orlistat
High-fat diet
Fat digestion
Issue Date: 2011
Publisher: Georg Thieme
Publisher version:
ISSN: 0032-0943
Citation: de la Garza AL, Milagro FI, Boque N, Campion J, Martinez JA. Natural inhibitors of pancreatic lipase as new players in obesity treatment. Planta Med 2011 May;77(8):773-785.
Obesity is a multifactorial disease characterized by an excessive weight for height due to an enlarged fat deposition such as adipose tissue, which is attributed to a higher calorie intake than the energy expenditure. The key strategy to combat obesity is to prevent chronic positive impairments in the energy equation. However, it is often difficult to maintain energy balance, because many available foods are high-energy yielding, which is usually accompanied by low levels of physical activity. The pharmaceutical industry has invested many efforts in producing antiobesity drugs; but only a lipid digestion inhibitor obtained from an actinobacterium is currently approved and authorized in Europe for obesity treatment. This compound inhibits the activity of pancreatic lipase, which is one of the enzymes involved in fat digestion. In a similar way, hundreds of extracts are currently being isolated from plants, fungi, algae, or bacteria and screened for their potential inhibition of pancreatic lipase activity. Among them, extracts isolated from common foodstuffs such as tea, soybean, ginseng, yerba mate, peanut, apple, or grapevine have been reported. Some of them are polyphenols and saponins with an inhibitory effect on pancreatic lipase activity, which could be applied in the management of the obesity epidemic.
Permanent link:
Appears in Collections:DA - Farmacia - CAFT - Línea Especial de Nutrición
DA - Farmacia - CAFT - Artículos de revista

Files in This Item:
File:  Planta medica2011.pdf
Size:  299,78 kB
Format:  Adobe PDF
 View / Open 
File:  Figura 1 planta medica.tif
Size:  609,51 kB
Format:  TIFF
 View / Open 
File:  Figure 2 Planta medica.jpg
Size:  49,03 kB
Format:  JPEG
Thumbnail Thumbnail
 View / Open 
File:  Figure 3 planta medica.jpg
Size:  57,56 kB
Format:  JPEG
Thumbnail Thumbnail
 View / Open 

Items in Dadun are protected by copyright, with all rights reserved, unless otherwise indicated.