Pharmacokinetic/pharmacodynamic modeling of the antinociceptive effects of (+)-tramadol in the rat: role of cytochrome P450 2D activity
Keywords:
Antinociceptive properties
Pharmacokinetic
Pharmacodynamic
Rat
Publisher:
American Society for Pharmacology and Experimental Therapeutics
Citation:
Garrido MJ, Sayar O, Segura C, Rapado J, Dios-Vieitez MC, Renedo MJ, et al. Pharmacokinetic/pharmacodynamic modeling of the antinociceptive effects of (+)-tramadol in the rat: role of cytochrome P450 2D activity. J Pharmacol Exp Ther 2003 May;305(2):710-718.
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