Full metadata record
DC Field | Value | Language |
---|---|---|
dc.creator | Melero, I. (Ignacio) | - |
dc.creator | Mazzolini, G. (Guillermo) | - |
dc.creator | Narvaiza, I. (Íñigo) | - |
dc.creator | Qian, C. (Cheng) | - |
dc.creator | Chen, L. (Lieping) | - |
dc.creator | Prieto, J. (Jesús) | - |
dc.date.accessioned | 2012-04-24T15:56:39Z | - |
dc.date.available | 2012-04-24T15:56:39Z | - |
dc.date.issued | 2001 | - |
dc.identifier.citation | Melero I, Mazzolini G, Narvaiza I, Qian C, Chen L, Prieto J. IL-12 gene therapy for cancer: in synergy with other immunotherapies. Trends Immunol 2001 Mar;22(3):113-115. | es_ES |
dc.identifier.issn | 1471-4981 | - |
dc.identifier.uri | https://hdl.handle.net/10171/21779 | - |
dc.description.abstract | In preclinical models of cancer, gene therapy with interleukin 12 (IL-12) has reached unprecedented levels of success when combined with immunotherapy approaches such as gene transfer of other cytokines and/or chemokines, costimulatory molecules or adoptive cell therapy. These combinations have been found to produce synergistic rather than additive effects. Meanwhile, IL-12 gene therapy is beginning clinical testing as a single agent, but combination strategies are at hand. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Gene therapy | es_ES |
dc.subject | Interleukin-12 | es_ES |
dc.subject | Immunotherapy | es_ES |
dc.subject | Cancer | es_ES |
dc.subject | Chemokines | es_ES |
dc.subject | Costimulation | es_ES |
dc.subject | Dendritic cells | es_ES |
dc.title | IL-12 gene therapy for cancer: in synergy with other immunotherapies | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherversion | http://www.sciencedirect.com/science/article/pii/S147149060001824X | es_ES |
dc.type.driver | info:eu-repo/semantics/article | es_ES |
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