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Dadun > Depósito Académico > CIMA (Centro de Investigación Médica Aplicada) > Área de Ciencias Cardiovasculares > Cardiopatía hipertensiva > DA - CIMA - Cardiovasculares - Cardiopatía hipertensiva - Artículos de Revista >

Involvement of cardiomyocyte survival-apoptosis balance in hypertensive cardiac remodeling
Autor(es) : Fortuño, M.A. (María Antonia)
Lopez, N. (Natalia)
Gonzalez, A. (Arantxa)
Diez, J. (Javier)
Palabras clave : Apoptosis/physiology
Cardiomegaly/physiopathology
Hypertension/physiopathology
Myocytes, Cardiac/pathology
Ventricular Remodeling/physiology
Fecha incorporación: 2003
Editorial : Expert Reviews
Versión del editor: http://bit.ly/IwRIbw
ISSN: 1744-8344
Cita: Fortuno MA, Lopez N, Gonzalez A, Diez J. Involvement of cardiomyocyte survival-apoptosis balance in hypertensive cardiac remodeling. Expert Rev Cardiovasc Ther 2003 Jul;1(2):293-307.
Resumen
The balance between cell death and cell survival is a tightly controlled process, especially in terminally differentiated cells, such as the cardiomyocyte. Accumulating data support a role for cardiomyocyte apoptosis in the development of several cardiac diseases, including the transition from hypertensive compensatory hypertrophy to heart failure. This review briefly summarizes the status of the knowledge regarding the death-survival balance of cardiomyocytes in the context of hypertensive heart disease. Several molecular and cellular aspects as well as the most relevant pathophysiological implications are presented. Moreover, diagnosis tools under development and the possibilities for pharmacological intervention are also examined.
Enlace permanente: http://hdl.handle.net/10171/21899
Aparece en las colecciones: DA - CIMA - Servicios de apoyo - Biobanco - Artículos de revista
DA - CIMA - Cardiovasculares - Cardiopatía hipertensiva - Artículos de Revista

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