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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.creator | Hermida, J. (José) | - |
dc.creator | Lopez, F.L. (Faye L.) | - |
dc.creator | Montes, R. (Ramón) | - |
dc.creator | Matsushita, K. (Kunihiro) | - |
dc.creator | Astor, B.C. (Brad C.) | - |
dc.creator | Alonso, A. (Alvaro) | - |
dc.date.accessioned | 2012-05-09T11:09:28Z | - |
dc.date.available | 2012-05-09T11:09:28Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Hermida J, Lopez FL, Montes R, Matsushita K, Astor BC, Alonso A. Usefulness of high-sensitivity C-reactive protein to predict mortality in patients with atrial fibrillation (from the Atherosclerosis Risk In Communities [ARIC] Study). Am J Cardiol 2012 Jan 1;109(1):95-99. | es_ES |
dc.identifier.issn | 1879-1913 | - |
dc.identifier.uri | https://hdl.handle.net/10171/21976 | - |
dc.description.abstract | High-sensitivity C-reactive protein (hs-CRP) is a marker for the risk of cardiovascular and overall mortality. However, information about the association between hs-CRP and mortality in patients with atrial fibrillation is scarce. A total of 293 participants of the Atherosclerosis Risk In Communities study with a history of AF and hs-CRP levels available were studied. During a median follow-up of 9.4 years, 134 participants died (46%). The hazard ratio of all-cause mortality associated with the highest versus the lowest tertile of hs-CRP was 2.52 (95% confidence interval 1.49 to 4.25) after adjusting for age, gender, history of cardiovascular diseases, and cardiovascular risk factors. A similar trend was observed for cardiovascular mortality (57 events; hazard ratio 1.90, 95% confidence interval 0.81 to 4.45). The Congestive heart failure, Hypertension, Age >75 years, Diabetes, and previous Stroke or transient ischemic attack (CHADS2) score was also associated with all-cause and cardiovascular mortality, with an adjusted hazard ratio of 3.39 (95% confidence interval 1.91 to 6.01) and 8.71 (95% confidence interval 2.98 to 25.47), respectively, comparing those with a CHADS2 score >2 versus a CHADS2 score of 0. Adding hs-CRP to a predictive model including the CHADS2 score was associated with an improvement of the C-statistic for total mortality (from 0.627 to 0.677) and for cardiovascular mortality (from 0.700 to 0.718). In conclusion, high levels of hs-CRP constitute an independent marker for the risk of mortality in patients with atrial fibrillation. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | info:eu-repo/semantics/closedAccess | - |
dc.subject | Atherosclerosis/epidemiology | es_ES |
dc.subject | Atrial Fibrillation/blood | es_ES |
dc.subject | C-Reactive Protein/metabolism | es_ES |
dc.title | Usefulness of high-sensitivity C-reactive protein to predict mortality in patients with atrial fibrillation (from the Atherosclerosis Risk In Communities [ARIC] Study) | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherversion | http://www.sciencedirect.com/science/article/pii/S0002914911025549 | es_ES |
dc.type.driver | info:eu-repo/semantics/article | es_ES |
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