Full metadata record
DC Field | Value | Language |
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dc.creator | Kloch-Badelek, M. (Malgorzata) | - |
dc.creator | Kuznetsova, T. (Tatiana) | - |
dc.creator | Sakiewicz, W. (Wojciech) | - |
dc.creator | Tikhonoff, V. (Valerie) | - |
dc.creator | Ryabikov, A. (Andrew) | - |
dc.creator | Gonzalez, A. (Arantxa) | - |
dc.creator | Lopez-Salazar, M.B. (María Begoña) | - |
dc.creator | Thijs, L. (Lutgarde) | - |
dc.creator | Jin, Y. (Yu) | - |
dc.creator | Malyutina, S. (Sofía) | - |
dc.creator | Stolarz-Skrzypek, K. (Katarzyna) | - |
dc.creator | Casiglia, E. (Edoardo) | - |
dc.creator | Diez-Martinez, J. (Javier) | - |
dc.creator | Narkiewicz, K. (Krzysztof) | - |
dc.creator | Kawecka-Jaszcz, K. (Kalina) | - |
dc.creator | Staessen, J.A. (Jan A.) | - |
dc.date.accessioned | 2012-05-11T18:19:28Z | - |
dc.date.available | 2012-05-11T18:19:28Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Kloch-Badelek M, Kuznetsova T, Sakiewicz W, Tikhonoff V, Ryabikov A, Gonzalez A, et al. Prevalence of left ventricular diastolic dysfunction in European populations based on cross-validated diagnostic thresholds. Cardiovasc Ultrasound 2012 Mar 19;10(1):10. | es_ES |
dc.identifier.issn | 1476-7120 | - |
dc.identifier.uri | https://hdl.handle.net/10171/22024 | - |
dc.description.abstract | BACKGROUND: Different diagnostic criteria limit comparisons between populations in the prevalence of diastolic left ventricular (LV) dysfunction. We aimed to compare across populations age-specific echocardiographic criteria for diastolic LV dysfunction as well as their correlates and prevalence. METHODS: We measured the E and A peaks of transmitral blood flow by pulsed wave Doppler and the e' and a' peaks of mitral annular velocities by tissue Doppler imaging (TDI) in 2 cohorts randomly recruited in Belgium (n = 782; 51.4% women; mean age, 51.1 years) and in Italy, Poland and Russia (n = 476; 55.7%; 44.5 years). RESULTS: In stepwise regression, the multivariable-adjusted correlates of the transmitral and TDI diastolic indexes were similar in the 2 cohorts and included sex, age, body mass index, blood pressure and heart rate. Similarly, cut-off limits for the E/A ratio (2.5th percentile) and E/e' ratio (97.5th percentile) in 338 and 185 reference subjects free from cardiovascular risk factors respectively selected from both cohorts were consistent within 0.02 and 0.26 units (median across 5 age groups). The rounded 2.5th percentile of the E/A ratio decreased by ~0.10 per age decade in these apparently healthy subjects. The reference subsample provided age-specific cut-off limits for normal E/A and E/e' ratios. In the 2 cohorts combined, diastolic dysfunction groups 1 (impaired relaxation), 2 (possible elevated LV filling pressure) and 3 (elevated E/e' and abnormally low E/A) encompassed 114 (9.1%), 135 (10.7%), and 40 (3.2%) subjects, respectively. CONCLUSIONS: The age-specific criteria for diastolic LV dysfunction were highly consistent across the study populations with an age-standardized prevalence of 22.4% vs. 25.1%. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | BioMed Central | es_ES |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/294713 | - |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Ventricular Dysfunction, Left/etiology | es_ES |
dc.subject | European populations | es_ES |
dc.title | Prevalence of left ventricular diastolic dysfunction in European populations based on cross-validated diagnostic thresholds | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherversion | http://www.cardiovascularultrasound.com/content/10/1/10/abstract | es_ES |
dc.type.driver | info:eu-repo/semantics/article | es_ES |
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