Full metadata record
DC Field | Value | Language |
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dc.creator | Paramo, J.A. (José Antonio) | - |
dc.creator | Olavide, I. (Isidro) | - |
dc.creator | Barba, J. (Joaquín) | - |
dc.creator | Montes, R. (Ramón) | - |
dc.creator | Panizo, C. (Carlos) | - |
dc.creator | Muñoz, M.C. (María Carmen) | - |
dc.creator | Rocha, E. (Eduardo) | - |
dc.date.accessioned | 2012-05-30T15:11:12Z | - |
dc.date.available | 2012-05-30T15:11:12Z | - |
dc.date.issued | 1998 | - |
dc.identifier.citation | Paramo JA, Olavide I, Barba J, Montes R, Panizo C, Munoz MC, et al. Long-term cardiac rehabilitation program favorably influences fibrinolysis and lipid concentrations in acute myocardial infarction. Haematologica 1998 Jun;83(6):519-524. | es_ES |
dc.identifier.issn | 1592-8721 | - |
dc.identifier.uri | https://hdl.handle.net/10171/22332 | - |
dc.description.abstract | BACKGROUND AND OBJECTIVE: The control of well-known atherosclerotic risk factors represents the optimal strategy in the prevention of acute coronary syndromes. It was the aim of this work to analyze the effects of a long-term cardiac rehabilitation program on the changes of fibrinolysis parameters and plasma lipid profile in coronary patients. DESIGN AND METHODS: The study was carried out in 30 (M/F:22/8, mean age 47 years) survivors of a first acute myocardial infarction (AMI) and in 30 healthy controls who underwent a cardiac rehabilitation program (9 months duration). Samples were taken before, at 3 and 9 months after the beginning of the program to measure: tissue-type plasminogen activator (t-PA) antigen and plasminogen activator inhibitor (PAI-1) activity and antigen. A lipid profile including cholesterol (both HDL and LDL) and lipoprotein(a) was also assessed. The Wilcoxon and Mann-Whitney tests were used for statistical comparisons. RESULTS: There was a marked decrease of functional PAI-1 after 3 and 9 months as compared with baseline in AMI patients (p < 0.01). Results showed a significant increase of HDL-cholesterol (p < 0.01) and decrease of lipoprotein(a) levels after the exercise program (p < 0.01). INTERPRETATION AND CONCLUSIONS: The cardiac rehabilitation program improved fibrinolysis, by reducing the functional levels of PAI-1, and ameliorated the lipid profile by decreasing lipoprotein(a) and increasing HDL-cholesterol in patients with AMI. A long-term cardiac rehabilitation has positive effects on some risk factors for coronary disease. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Ferrata Storti Foundation | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Exercise | es_ES |
dc.subject | Acute myocardial infarction | es_ES |
dc.subject | Fibrinolysis | es_ES |
dc.subject | PAI-1 | es_ES |
dc.subject | Lipoprotein(a) | es_ES |
dc.title | Long-term cardiac rehabilitation program favorably influences fibrinolysis and lipid concentrations in acute myocardial infarction | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherversion | http://www.haematologica.org/content/83/6/519 | es_ES |
dc.type.driver | info:eu-repo/semantics/article | es_ES |
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