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Intraductal papillary mucinous neoplasms (IPMN) of the pancreas: clinico-pathologic results
Otros títulos : ntraductal neoplasias mucinosas papilares (IPMN) de la páncreas: resultados clínico-patológicas
Autor(es) : Cienfuegos, J.A. (Javier A.)
Rotellar, F. (Fernando)
Marti-Cruchaga, P. (Pablo)
Valenti, V. (Victor)
Zozaya, G. (Gabriel)
Bueno, A. (Álvaro)
Pedano, N. (Nicolás)
Lozano, M.D. (María Dolores)
Sola, J.J. (Jesús J.)
Pardo, F. (Fernando)
Palabras clave : Intraductal papillary mucinous neoplasm
Invasive carcinoma
Prognosis factors
Fecha incorporación: 2010
Editorial : The Spanish Society of Digestive Pathology
Versión del editor: http://www.grupoaran.com/mrmUpdate/lecturaPDFfromXML.asp?IdArt=4618812&TO=RVN&Eng=1
ISSN: 1130-0108
Cita: A-Cienfuegos J, Rotellar F, Marti-Cruchaga P, Valenti V, Zozaya G, Bueno A, et al. Intraductal papillary mucinous neoplasms (IPMN) of the pancreas: clinico-pathologic results. Rev Esp Enferm Dig 2010 May;102(5):314-320.
Background: intraductal papillary mucinous neoplasm (IPMN) shows a series of lesions which evolve from benign lesions –adenoma– to invasive carcinoma. Aim: to analyze the clinical and pathological results of 15 patients diagnosed of IPMN, and surgically treated according to the guidelines of International Consensus Conference. Material and methods: a retrospective analysis of 15 patients surgically treated between March 1993 and September 2009, according to the International Consensus recommendation. Demographic, diagnostic tools, surgical report, pathologic database and actuarial survival were analyzed with a follow-up from one and a half month through nine years. Results: 6 patients underwent pancreaticoduodenectomies, 4 total pancreatectomies, 2 body or central pancreatectomies, 2 partial pancreatectomies (enucleation) and 1 distal pancreatectomy. A morbidity of 46 and 0% hospital mortality were assessed, with a median length hospital stay of 10 days. In five cases, the IPMN was combined type (both main and branch pancreatic ducts involved) in four main duct-type and branch duct-type in the another six as well. Several atypia (IPMN carcinoma in situ) was observed in 2 patients and invasive carcinoma with negative lymph nodes was identified in 3 patients. A patient without invasive carcinoma died at 66 months of follow-up for pancreas adenocarcinoma. The actuarial survival up to recurrence or death was 105,133 months with a range of follow-up from 1 month and a half until 9 years. Conclusions: IPMN main duct or mixed type warrants complete resection due to its incidence of invasive carcinoma or precursor lesions of malignancy as well. Due to its multifocal pattern, patients should be followed in long-term surveillance. The management of asymptomatic IPMN type branch less than 3 cm is controversial.
Enlace permanente: http://hdl.handle.net/10171/22479
Aparece en las colecciones: DA - Medicina - Cirugía General - Artículos de revista
DA - CUN - Cirugía general y digestiva - Artículos de revista

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Fichero:  Rev Esp Enferm Dig 2010. 314.pdf
Tamaño:  374,08 kB
Formato:  Adobe PDF
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