Dianas quirúrgicas en el tratamiento de enfermedades psiquiátricas. Desde el movimiento a las emociones
Other Titles: 
Surgical targets in Psychiatric disorders. From movement to emotions
Keywords: 
Deep brain stimulation
Parkinson´s disease
Obsessive-compulsive disorder
Depression
Issue Date: 
2011
Publisher: 
Sociedad Española de Neurocirugía
ISSN: 
1130-1473
Citation: 
Guridi J, Aldave G. Dianas quirúrgicas en el tratamiento de enfermedades psiquiátricas. Desde el movimiento a las emociones. Neurocirugia (Astur) 2011 Feb;22(1):5-22.
Abstract
Deep brain stimulation (DBS) for psychiatric disorders refractory to conventional treatments are currently been performed based in the knowledgment obtained in the motor disorder surgery and mainly in Parkinson´s disease. Depression, obsessive-compulsive disorder (OCD) and Tourette syndrome, all of them are cortico-striato-thalamo-cortical pathological process involved in the limbic loop of the basal ganglia. This review describes the different targets in these pathological neuro-psychiatric disorders. For OCD there are currently two targets, ventral striatum (VS) Accumbens nucleus (Nacc) and the subthalamic nucleus (STN). In refractory depression the subgenual area (25 Brodmann area) and VS/Nacc. For Tourette syndrome the ventralis oralis internus and centromedianum/ parafascicularis of the thalamus (Voi and CM/Pf) and the internal part of the globus pallidus (GPi). Currently there are no specific surgical target for each pathological disorder because clinical results reported are very similar after stimulation surgery. In other point, a selected surgical target also may improve different pathologies.

Files in This Item:
File: 
Neurocirugia 2011.5.pdf
Description: 
Size: 
793,49 kB
Format: 
Adobe PDF


Items in Dadun are protected by copyright, with all rights reserved, unless otherwise indicated.