Estudio ecocardiográfico y de la concentración de NT-proBNP en pacientes diabéticos tipo 2 con y sin cardiopatía isquémica
Otros títulos : 
Echocardiographic findings and NT-proBNP level in type-2 diabetic patients with and without ischemic heart disease
Palabras clave : 
Diabetes mellitus, type 2/blood/complications
Myocardial ischemia/blood/complications/ultrasonography
Natriuretic peptide, brain/blood
Fecha incorporación: 
2009
Editorial : 
Elsevier España
ISSN: 
0300-8932
Cita: 
Castano Rodriguez S, Coma-Canella I, Lopez Salazar B, Barba Cosials J. Estudio ecocardiográfico y de la concentración de NT-proBNP en pacientes diabéticos tipo 2 con y sin cardiopatía isquémica. Rev Esp Cardiol 2009 Oct;62(10):1184-1188
Resumen
The aim of this study was to determine whether there are differences in echocardiographic findings or in the level of a biochemical marker (i.e. N-terminal probrain natriuretic peptide [NT-proBNP]) between controls and type-2 diabetic patients with or without ischemic heart disease. Echocardiography was used to assess left ventricular function and morphology. In addition, the plasma NT-proBNP concentration was measured. The prevalence of diastolic dysfunction was greater in diabetics without ischemic heart disease than in controls (88% vs. 74%, respectively; P< .001) and the NT-proBNP concentration was higher (350.6+/-197.8 vs. 281.7+/-190.4 fmol/mL; P< .001). Diabetics with ischemic heart disease had a higher NT-proBNP concentration than those without (720.4+/-278.1 vs. 350.6+/-197.8 fmol/mL, respectively; P< .001). An NT-proBNP concentration >490 fmol/mL had a sensitivity of 84% and a specificity of 75% for detecting ischemic heart disease in diabetics.

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Fichero: 
Rev Esp Cardiol 2009. 1148.pdf
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85,93 kB
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