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Fibrosing cholestatic hepatitis following cytotoxic chemotherapy for small-cell lung cancer
Authors: Ceballos-Viro, J. (Jaime)
Lopez-Picazo, J.M. (José M.)
Perez-Gracia, J.L. (José Luis)
Sola, J.J. (Jesús J.)
Aisa, G. (Gregorio)
Gil-Bazo, I. (Ignacio)
Keywords: Fibrosing cholestatic hepatitis
Lung cancer
Issue Date: 2009
Publisher: Baishideng Publishing Group Co. Limited
Publisher version:
ISSN: 1007-9327
Citation: Ceballos-Viro J, Lopez-Picazo JM, Perez-Gracia JL, Sola JJ, Aisa G, Gil-Bazo I. Fibrosing cholestatic hepatitis following cytotoxic chemotherapy for small-cell lung cancer. World J Gastroenterol 2009 May 14;15(18):2290-2292
Fibrosing cholestatic hepatitis (FCH) is a variant of viral hepatitis reported in hepatitis B virus or hepatitis C virus infected liver, renal or bone transplantation recipients and in leukemia and lymphoma patients after conventional cytotoxic chemotherapy. FCH constitutes a well-described form of fulminant hepatitis having ex-- of a 49-year-old patient diagnosed with small-cell lung cancer who developed this condition following conventional chemotherapy-induced immunosuppression. This conventional chemotherapy for a solid tumor. In addition to a detailed report of the case, a physiopathological examination of this potentially life-threatening condition and its treatment options are discussed.
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