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dc.creatorPastor, M.A. (María A.)-
dc.creatorValencia-Ustarroz, M. (Miguel)-
dc.creatorArtieda, J. (Julio)-
dc.creatorAlegre, M. (Manuel)-
dc.creatorMasdeu, J. (José)-
dc.date.accessioned2012-07-02T08:38:09Z-
dc.date.available2012-07-02T08:38:09Z-
dc.date.issued2007-
dc.identifier.citationPastor MA, Valencia M, Artieda J, Alegre M, Masdeu JC. Topography of cortical activation differs for fundamental and harmonic frequencies of the steady-state visual-evoked responses. An EEG and PET H215O study. Cereb Cortex 2007 Aug;17(8):1899-1905.es_ES
dc.identifier.issn1047-3211-
dc.identifier.urihttp://hdl.handle.net/10171/22761-
dc.description.abstractIn humans, visual flicker stimuli of graded frequency (2--90 Hz) elicit an electroencephalographic (EEG) steady-state visual-evoked response (SSVER) with the same fundamental frequency as the stimulus and, in addition, a series of harmonic responses. The fundamental component of the SSVER is generated by increased synaptic activity in primary visual cortex (V1). We set out to determine the cortical origin of the harmonic responses in humans. For this purpose, we recorded the SSVERs at 5 different frequencies (5, 10, 15, 25, and 40 Hz) and measured regional cerebral blood flow (rCBF) with positron emission tomography-H15 2 O at rest and during visual stimulation at the same frequencies. The rCBF contrast weighted by the amplitude of the SSVERs first harmonics showed activation of a swath of cortex perpendicular to V1, including mostly the inferior half of the parietooccipital sulcus. This area overlapped minimally with the primary visual cortex activated by the fundamental frequency. A different method, estimating EEG cortical source current density with lowresolution brain electromagnetic tomography, gave the same results. Our finding suggests that the inferior portion of the banks of the parieto-occipital sulci contains association visual cortex involved in the procparieto-occipital sulcus,es_ES
dc.language.isoenges_ES
dc.publisherOxford University Presses_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectParieto-occipital sulcuses_ES
dc.subjectVisual cortexes_ES
dc.subjectVisual-evoked potentialses_ES
dc.titleTopography of Cortical Activation Differs for Fundamental and Harmonic Frequencies of the Steady-State Visual-Evoked Responses. An EEG and PET H15 2 O Studyes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttp://cercor.oxfordjournals.org/content/17/8/1899.full.pdf+htmles_ES
dc.type.driverinfo:eu-repo/semantics/articlees_ES

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