Malignant atrophic papulosis. A report of two cases with altered fibrinolysis and platelet function
Palabras clave : 
Blood Platelet Disorders/complications
Skin Diseases, Vascular/complications
Fecha de publicación: 
1993
Editorial : 
Wiley-Blackwell
ISSN: 
1365-2230
Cita: 
Vazquez-Doval FJ, Ruiz de Erenchun F, Paramo JA, Quintanilla E. Malignant atrophic papulosis. A report of two cases with altered fibrinolysis and platelet function. Clin Exp Dermatol 1993 Sep;18(5):441-444.
Resumen
Malignant atrophic papulosis is a systemic vaso-occlusive disorder characterized by typical skin lesions. We report two new cases with impairment of blood fibrinolytic activity and alterations in platelet function. The first case showed an increase in plasminogen activator inhibitor-1 (PAI-1) activity, and the second case had a decrease in platelet aggregation induced by adenosine diphosphate and adrenaline but normal with collagen. The impairment of blood fibrinolytic activity and platelet aggregation may have pathogenic and therapeutic implications in malignant atrophic papulosis.

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ClinExpDermatol1993_18441.pdf
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