Full metadata record
DC Field | Value | Language |
---|---|---|
dc.creator | Beunza, J.J. (Juan José) | - |
dc.creator | Martinez-Gonzalez, M.A. (Miguel Ángel) | - |
dc.creator | Bes-Rastrollo, M. (Maira) | - |
dc.creator | Nuñez-Cordoba, J.M. (Jorge M.) | - |
dc.creator | Toledo, E. (Estefanía) | - |
dc.creator | Alonso, A. (Alvaro) | - |
dc.date.accessioned | 2012-07-06T08:22:30Z | - |
dc.date.available | 2012-07-06T08:22:30Z | - |
dc.date.issued | 2010 | - |
dc.identifier.citation | Beunza JJ, Martinez-Gonzalez MA, Bes-Rastrollo M, Nunez-Cordoba JM, Toledo E, Alonso A. Aspirin, non-aspirin analgesics and the risk of hypertension in the SUN cohort. Rev Esp Cardiol 2010 Mar;63(3):286-293. | es_ES |
dc.identifier.issn | 0300-8932 | - |
dc.identifier.uri | https://hdl.handle.net/10171/22848 | - |
dc.description.abstract | The use of aspirin and non-aspirin analgesics has been associated with changes in blood pressure. The aim of this study was to investigate prospectively the association between the regular use of aspirin and non-aspirin analgesics and the incidence of hypertension. METHODS: The SUN project is an ongoing, continuously expanding, prospective cohort of Spanish university graduates initially free of hypertension, cardiovascular disease, diabetes and cancer; 9986 (mean age 36 years) were recruited during 1999-2005 and followed up for a mean of 51 months. Regular aspirin and non-aspirin analgesic use and the presence of other risk factors for hypertension were assessed by questionnaire at baseline, and the incidence of hypertension was assessed using biennial follow-up questionnaires. RESULTS: In total, 543 new cases of hypertension were identified during follow-up. Regular aspirin use (i.e. 2 or more days/week) was associated with a higher risk of hypertension (hazard ratio=1.45; 95% confidence interval, 1.02-2.04) after adjustment for various confounding factors. Regular use of non-aspirin analgesic drugs was also associated with a higher risk of hypertension (hazard ratio=1.69; 95% confidence interval, 1.28-2.23). CONCLUSIONS: The regular use of aspirin and non-aspirin analgesics were both associated with an increased risk of developing hypertension, independently of other risk factors. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier España | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Anti-Inflammatory agents, Non-steroidal/adverse effects | es_ES |
dc.subject | Aspirin/adverse effects | es_ES |
dc.subject | Hypertension/chemically induced/epidemiology | es_ES |
dc.title | Aspirin, non-aspirin analgesics and the risk of hypertension in the SUN cohort. | es_ES |
dc.title.alternative | La aspirina, analgésicos sin aspirina y el riesgo de hipertensión arterial en la cohorte de SUN | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.type.driver | info:eu-repo/semantics/article | es_ES |
dc.identifier.doi | http://dx.doi.org/10.1016/S1885-5857(10)70061-X | es_ES |
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