Recognition and management of hereditary colorectal cancer syndromes
Other Titles: 
El reconocimiento y la gestión de los síndromes hereditarios de cáncer colorrectal
Keywords: 
Colorectal neoplasms, hereditary nonpolyposis/diagnosis/drug therapy/epidemiology/genetics/surgery
Endometrial neoplasms/genetics/surgery
Cyclooxygenase 2 Inhibitors/therapeutic use
Issue Date: 
2009
Publisher: 
The Spanish Society of Digestive Pathology
ISSN: 
1130-0108
Citation: 
Herraiz M, Muñoz-Navas M. Recognition and management of hereditary colorectal cancer syndromes. Rev Esp Enferm Dig 2009 Feb;101(2):125-132.
Abstract
Over 1,900 colorectal tumors will arise in association with a hereditary colorectal cancer syndrome in Spain in 2009. The genetic defects responsible for the most common syndromes have been discovered in recent years. Genetic testing helps diagnose affected individuals and allows identification of individuals at-risk. Colonoscopy and prophylactic colectomy decrease colorectal cancer incidence and overall mortality in patients with hereditary colon cancer. Extracolonic tumors are frequent in these syndromes, so specific surveillance strategies should be offered

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