Full metadata record
DC Field | Value | Language |
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dc.creator | Spada, C. (Cristiano) | - |
dc.creator | Muñoz-Navas, M. (Miguel) | - |
dc.creator | Hassan, C. (Cesare) | - |
dc.creator | Neuhaus, H. (Horst) | - |
dc.creator | Deviere, J. (Jacques) | - |
dc.creator | Fockens, P. (Paul) | - |
dc.creator | Coron, E. (Emmanuel) | - |
dc.creator | Gay, G. (Gerard) | - |
dc.creator | Toth, E. (Ervin) | - |
dc.creator | Riccioni, M.E. (Maria Elena) | - |
dc.creator | Carretero, C. (Cristina) | - |
dc.creator | Charton, J.P. (Jean P.) | - |
dc.creator | Gossum, A. (Andre) van | - |
dc.creator | Wientjes, C.A. (Caroline A.) | - |
dc.creator | Sacher-Huvelin, S. (Sylvie) | - |
dc.creator | Delvaux, M. (Michel) | - |
dc.creator | Nemeth, A. (Artur) | - |
dc.creator | Petruzziello, L. (Lucio) | - |
dc.creator | Prieto-Martínez, C. (Carlos) | - |
dc.creator | Mayershofer, R. (Rupert) | - |
dc.creator | Aminejab, L. (Leila) | - |
dc.creator | Dekker, E. (Evelien) | - |
dc.creator | Galmiche, J.P. (Jean-Paul) | - |
dc.creator | Frederic, M. (Muriel) | - |
dc.creator | Johansson, G.W. (Gabriele Wurn) | - |
dc.creator | Cesaro, P. (Paola) | - |
dc.creator | Costamagna, G. (Guido) | - |
dc.date.accessioned | 2012-11-21T09:23:54Z | - |
dc.date.available | 2012-11-21T09:23:54Z | - |
dc.date.issued | 2011 | - |
dc.identifier.citation | Spada C, Hassan C, Munoz-Navas M, Neuhaus H, Deviere J, Fockens P, et al. Second-generation colon capsule endoscopy compared with colonoscopy. Gastrointest Endosc 2011 9;74(3):581-589.e1. | es_ES |
dc.identifier.issn | 0016-5107 | - |
dc.identifier.uri | https://hdl.handle.net/10171/23744 | - |
dc.description.abstract | Colon capsule endoscopy (CCE) represents a noninvasive technology that allows visualization of the colon without requiring sedation and air insufflation. A second-generation colon capsule endoscopy system (PillCam Colon 2) (CCE-2) was developed to increase sensitivity for colorectal polyp detection compared with the first-generation system. OBJECTIVE: To assess the feasibility, accuracy, and safety of CCE-2 in a head-to-head comparison with colonoscopy. DESIGN AND SETTING: Prospective, multicenter trial including 8 European sites. PATIENTS: This study involved 117 patients (mean age 60 years). Data from 109 patients were analyzed. INTERVENTION: CCE-2 was prospectively compared with conventional colonoscopy as the criterion standard for the detection of colorectal polyps that are >/=6 mm or masses in a cohort of patients at average or increased risk of colorectal neoplasia. Colonoscopy was independently performed within 10 hours after capsule ingestion or on the next day. MAIN OUTCOME MEASUREMENTS: CCE-2 sensitivity and specificity for detecting patients with polyps >/=6 mm and >/=10 mm were assessed. Capsule-positive but colonoscopy-negative cases were counted as false positive. Capsule excretion rate, level of bowel preparation, and rate of adverse events also were assessed. RESULTS: Per-patient CCE-2 sensitivity for polyps >/=6 mm and >/=10 mm was 84% and 88%, with specificities of 64% and 95%, respectively. All 3 invasive carcinomas were detected by CCE-2. The capsule excretion rate was 88% within 10 hours. Overall colon cleanliness for CCE-2 was adequate in 81% of patients. LIMITATIONS: Not unblinding the CCE-2 results at colonoscopy; heterogenous patient population; nonconsecutive patients. CONCLUSION: In this European, multicenter study, CCE-2 appeared to have a high sensitivity for the detection of clinically relevant polypoid lesions, and it might be considered an adequate tool for colorectal imaging. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Capsule Endoscopy/adverse effects | es_ES |
dc.subject | Colonic Polyps/diagnosis/pathology | es_ES |
dc.subject | Colonoscopy/adverse effects | es_ES |
dc.title | Second-generation colon capsule endoscopy compared with colonoscopy | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.type.driver | info:eu-repo/semantics/article | es_ES |
dc.identifier.doi | http://dx.doi.org/10.1016/j.gie.2011.03.1125 | es_ES |
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