Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.creator | Alava, E. (Enrique) de | - |
| dc.creator | Lozano, M.D. (María Dolores) | - |
| dc.creator | Sola, J. (Josu) | - |
| dc.creator | Panizo, A. (Ángel) | - |
| dc.creator | Idoate, M.A. (Miguel Ángel) | - |
| dc.creator | Martinez-Isla, C. (Carmen) | - |
| dc.creator | Forteza, J. (Jerónimo) | - |
| dc.creator | Sierrasesumaga, L. (Luis) | - |
| dc.creator | Pardo-Mindan, F.J. (Francisco Javier) | - |
| dc.date.accessioned | 2012-11-21T13:53:52Z | - |
| dc.date.available | 2012-11-21T13:53:52Z | - |
| dc.date.issued | 1998 | - |
| dc.identifier.citation | de Alava E, Lozano MD, Sola I, Panizo A, Idoate MA, Martinez-Isla C, et al. Molecular features in a biphenotypic small cell sarcoma with neuroectodermal and muscle differentiation. Hum Pathol 1998 Feb;29(2):181-184. | es_ES |
| dc.identifier.issn | 0046-8177, | - |
| dc.identifier.uri | https://hdl.handle.net/10171/23759 | - |
| dc.description.abstract | We report a case of a 13-year-old girl with soft tissue sarcoma of the hand, which showed muscle and neuroectodermal immunophenotypes. Molecular studies were performed on RNA collected from fine-needle aspiration (FNA) cytology and peripheral blood samples by nested reverse transcriptase-polymerase chain reaction (RT-PCR) and Southern blot analysis. This biphenotypic tumor showed simultaneous expression of EWS-FLI1 and PAX3-FKHR transcripts, specific of Ewing family tumors and alveolar rhabdomyosarcoma, respectively. Although childhood sarcomas with simultaneous muscle and neural differentiation have been described to have EWS-FLI1 transcripts, there are no reports of tumors with both transcripts. Cytological specimens are a good source of RNA for molecular studies | es_ES |
| dc.language.iso | eng | es_ES |
| dc.publisher | WB Saunders | es_ES |
| dc.rights | info:eu-repo/semantics/openAccess | es_ES |
| dc.subject | Muscle Neoplasms/genetics/immunology/pathology | es_ES |
| dc.subject | Sarcoma, Small Cell/genetics/immunology/pathology | es_ES |
| dc.subject | Tumor Markers, Biological/analysis | es_ES |
| dc.title | Molecular features in a biphenotypic small cell sarcoma with neuroectodermal and muscle differentiation | es_ES |
| dc.type | info:eu-repo/semantics/article | es_ES |
| dc.type.driver | info:eu-repo/semantics/article | es_ES |
| dc.identifier.doi | http://dx.doi.org/10.1016/S0046-8177(98)90230-1 | es_ES |
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