Karnofsky performance score in acute renal failure as a predictor of short-term survival
Keywords: 
Acute renal failure
Functional status
Karnofsky score
Mortality
Issue Date: 
2007
Publisher: 
Wiley-Blackwell
ISSN: 
1320-5358
Citation: 
Perez Valdivieso JR, Bes-Rastrollo M, Monedero P, De Irala J, Lavilla FJ. Karnofsky performance score in acute renal failure as a predictor of short-term survival. Nephrology (Carlton). 2007 Dec;12(6):533-538.
Abstract
Karnofsky Performance Scale Index (KPS) is a measure of functional status that allows patients to be classified according to their functional impairment. We aim to assess if the prior KPS may predict the risk of death among patients with acute renal failure (ARF). METHODS: A cohort of 668 consecutive patients who had been admitted in an university-affiliated hospital between June 2000 and June 2006, and had been diagnosed with ARF, were studied. Three hundred and eighty-six patients with ARF who matched at least one of the RIFLE (Risk, Injury, Failure, Loss and End stage) criteria on increased serum creatinine were included for subsequent analysis. The group was divided into four categories, according to different Karnofsky scores measured by a nephrologist (>or=80, 70, 60 and or=80 Karnofsky group. Adjusted odds ratios were 8.87 (95% confidence interval (CI) 3.03-25.99), 6.78 (95% CI 2.61-17.58) and 2.83 (95% CI 1.04-7.68), for Karnofsky groups of

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