Rose Bengal plate agglutination and counterimmunoelectrophoresis tests on spinal fluid in the diagnosis of Brucella meningitis
Keywords: 
Agglutination tests
Brucellosis diagnosis
Cerebrospinal fluid immunology
Counterimmunoelectrophoresis
Immunoelectrophoresis
Meningitis diagnosis
Issue Date: 
1978
Publisher: 
American Society for Microbiology
ISSN: 
0095-1137
Citation: 
Diaz R, Maravi-Poma E, Delgado G, Rivero A. Rose Bengal plate agglutination and counterimmunoelectrophoresis tests on spinal fluid in the diagnosis of Brucella meningitis. J Clin Microbiol 1978 Feb;7(2):236-237.
Abstract
Rose Bengal and counterimmunoelectrophoresis, two tests that detect antibodies against different structural antigens, when carried out on spinal fluid permitted rapid diagnosis of human Brucella meningitis. The Rose Bengal test was positive in five out of five patients studied, and counterimmunoelectrophoresis was positive in all but one. The Brucella meningitis was characterized by an increase of immunoglobulin G in the cerebrospinal fluid.

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