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dc.creatorZarranz, B. (Belén)-
dc.creatorJaso, A. (Andrés)-
dc.creatorLima, L.M. (Lidia M.)-
dc.creatorAldana, I. (Ignacio)-
dc.creatorMonge, A. (Antonio)-
dc.creatorMaurel, S. (Séverine)-
dc.creatorSauvain, M. (Michel)-
dc.date.accessioned2013-07-17T07:34:42Z-
dc.date.available2013-07-17T07:34:42Z-
dc.date.issued2006-
dc.identifier.citationZarranz B, Jaso A, Lima LM, Aldana I, Monge A, Maurel S, et al . Antiplasmodial activity of 3-trifluoromethyl-2-carbonylquinoxaline di-N-oxide derivatives. Rev Bras Cienc Farm, 2006 Sep;42(3):357-361es_ES
dc.identifier.isbn1516-9332-
dc.identifier.urihttps://hdl.handle.net/10171/29500-
dc.description.abstractThe in vitro antiplasmodial activity of some 3-trifluoromethyl-2-carbonylquinoxaline di-N-oxide derivatives is reported. The evaluation was performed on cultures of FcB1 strain (chloroquine-resistant) of P. falciparum and the most interesting compounds were then evaluated on MCF7 tumor cells in order to evaluate an index of selectivity. The 7-methyl (2b, 4b, 5b, 6b) and nonsubstituted (3c, 4c, 5c) quinoxaline 1,4-dioxide derivatives presented the best level of activity.es_ES
dc.language.isoenges_ES
dc.language.isospaes_ES
dc.publisherUniversidade de São Pauloes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectQuinoxalinees_ES
dc.subjectAntimalariales_ES
dc.subjectChloroquinees_ES
dc.subjectMCF7es_ES
dc.titleAntiplasmodial activity of 3-trifluoromethyl-2-carbonylquinoxaline di-N-oxide derivativeses_ES
dc.title.alternativeAtividade antimalárica de derivados di-N-óxido de 3-trifluorometil-2-carbonilquinoxalinaes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.type.driverinfo:eu-repo/semantics/articlees_ES
dc.identifier.doihttp://dx.doi.org/10.1590/S1516-93322006000300005es_ES

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