Development and evaluation of a rapid dipstick assay for serodiagnosis of acute human brucellosis

Smits, H.L. (Henk L.); Basahi, M.A. (M. A.); Diaz, R. (Ramón); Marrodan, T. (T.); Douglas, J.T. (James T.); Rocha, A. (Alice); Veerman, J. (Jaques); Zheludkov, M.M. (M. M.); Witte, O.W.M. (Olav W. M.); Jong, J. (Joop) de; Gussenhoven, G.C. (George C.); Goris, M.G.A. (Marga G. A.); Hoorn, M.A.W.G. (Menno A. W. G.) van der

Keywords:

Seroprevalence
Antibodies
Diagnosis
Disease
Jordan
Microbiology

Issue Date:

1999

Publisher:

American Society for Microbiology

ISSN:

0095-1137

Citation:

Smits HL, Basahi MA, Diaz R, Marrodan T, Douglas JT, Rocha A, et al. Development and evaluation of a rapid dipstick assay for serodiagnosis of acute human brucellosis. J Clin Microbiol 1999 Dec;37(12):4179-4182.

Abstract

A dipstick assay for the detection of brucella-specific immunoglobulin M antibodies was evaluated with 707 sera from 247 laboratory-confirmed brucellosis patients and 342 control sera from brucellosis-free individuals. These sera were collected from six different countries. The assay was found to be highly sensitive and specific. In addition, the test is easy to use and does not require specialized training or equipment, and the components are stable without a requirement for refrigeration. All of these factors make the test ideal for developing countries and rural settings.

URI:

https://hdl.handle.net/10171/29643

Appears in Collections:

DA - Medicina - Microbiología y Parasitología - Artículos de revista

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