Clinical features, pathophysiology, and treatment of levodopa-induced dyskinesias in Parkinson's disease
Palabras clave : 
Clinical features
Dyskinetic disorders
Parkinson's disease
Fecha de publicación: 
2012
Editorial : 
Hindawi Publishing Corporation
ISSN: 
2042-0080
Cita: 
Guridi J, González-Redondo R, Obeso JA. Clinical features, pathophysiology, and treatment of levodopa-induced dyskinesias in Parkinson's disease. Parkinsons Dis. 2012;2012:943159.
Resumen
Dyskinetic disorders are characterized by excess of motor activity that may interfere with normal movement control. In patients with Parkinson's disease, the chronic levodopa treatment induces dyskinetic movements known as levodopa-induced dyskinesias (LID). This paper analyzed the pathophysiology, clinical manifestations, pharmacological treatments, and surgical procedures to treat hyperkinetic disorders. Surgery is currently the only treatment available for Parkinson's disease that may improve both parkinsonian motor syndrome and LID. However, this paper shows the different mechanisms involved are not well understood.

Ficheros en este registro:
Fichero: 
Parkinsons D2012-943159.pdf
Descripción: 
Tamaño: 
681,4 kB
Formato: 
Adobe PDF


Los ítems de Dadun están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.