Full metadata record
DC Field | Value | Language |
---|---|---|
dc.creator | Lorente, M.D. (María Dolores) | - |
dc.creator | Marginet, C. (C.) | - |
dc.creator | Pujante, P. (P.) | - |
dc.date.accessioned | 2014-03-12T10:56:33Z | - |
dc.date.available | 2014-03-12T10:56:33Z | - |
dc.date.issued | 2007 | - |
dc.identifier.citation | Lorente MD, Marginet C, Pujante P. Osteoporosis: ¿Diagnóstico o signo de sospecha?. Rev Med Univ Navarra. 2007 Oct-Dec;51(4):9-11 | es_ES |
dc.identifier.issn | 0556-6177 | - |
dc.identifier.uri | https://hdl.handle.net/10171/35469 | - |
dc.description.abstract | Objetivo: Se presenta un caso clínico de un paciente varón de 52 años que acude a consulta de Neurología por referir en los últimos meses deterioro progresivo del estado general con deterioro cognitivo, espe- cialmente de memoria y funciones ejecutivas, debilidad proximal en las cuatro extremidades, dolor en zona lumbar y disminución de 10 cm de talla. Se realizó una densitometría ósea siendo diagnosticado de osteoporosis precoz. Resultados/conclusión: En la analítica se objetivó aumento del cortisol libre en orina (1725 g/24h), con ACTH detectable (89 pg/ml) compati- ble con síndrome de Cushing ACTH-dependiente. Se realizaron pruebas para diferenciar un posible origen hipofi sario o ectópico realizándose un cateterismo de senos petrosos (CSPI) dado que se trata de la prueba con mayor sensibilidad demostrada. INGLÉS: We present the case of a fifty-year-old male who presented at the Neurology Service. During the previous months he had noticed progressive cognitive deterioration, and particularly a loss of memory and executive abilities, as well as proximal weakness of the four limbs and lumbar tenderness. He had lost ten centimetres of height. A bone densitometry was performed, which showed early osteoporosis. RESULTS/CONCLUSIONS: The laboratory results showed an increase in urine cortisol excretion (1725 g/24h), with detectable plasma ACTH concentration (89 pg/ml), suggesting ACTH-dependent Cushing's syndrome, Additional tests were run in order to determine a hypothalamic or ectopic location of the syndrome. To this end, a bilateral inferior petrosal sinus sample (BIPSS) was performed for ACTH determination. BIPSS is the test that has been proven to have the best sensitivity to achieve differential diagnosis of ACTH-dependent Cushing's syndrome | es_ES |
dc.language.iso | spa | es_ES |
dc.publisher | Ediciones Universidad de Navarra | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Osteoporosis | es_ES |
dc.subject | Síndrome de Cushing, | es_ES |
dc.title | Osteoporosis: ¿Diagnóstico o signo de sospecha? | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherversion | https://revistas.unav.edu/index.php/revista-de-medicina | - |
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