Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.creator | Aldana, I. (Ignacio) | - |
| dc.creator | Monge, A. (Antonio) | - |
| dc.creator | Deharo, E. (Eric) | - |
| dc.creator | Pérez-Silanes, S. (Silvia) | - |
| dc.creator | Burguete, A. (Asunción) | - |
| dc.creator | Galiano, S. (Silvia) | - |
| dc.creator | Pabon, A. (Adriana) | - |
| dc.creator | Gil, A. (Ana) | - |
| dc.date.accessioned | 2014-04-08T09:58:37Z | - |
| dc.date.available | 2014-04-08T09:58:37Z | - |
| dc.date.issued | 2014-02-18 | - |
| dc.identifier.citation | Gil A, Pabón A, Galiano S, Burguete A, Pérez-Silanes S, Deharo E, et al. Synthesis, biological evaluation and structure-activity relationships of new quinoxaline derivatives as anti-Plasmodium falciparum agents. Molecules 2014 Feb 18;19(2):2166-2180 | es_ES |
| dc.identifier.issn | 1420-3049 | - |
| dc.identifier.uri | https://hdl.handle.net/10171/35725 | - |
| dc.description.abstract | We report the synthesis and antimalarial activities of eighteen quinoxaline and quinoxaline 1,4-di-N-oxide derivatives, eight of which are completely novel. Compounds 1a and 2a were the most active against Plasmodium falciparum strains. Structure-activity relationships demonstrated the importance of an enone moiety linked to the quinoxaline ring. | es_ES |
| dc.language.iso | eng | es_ES |
| dc.publisher | MDPI (Molecular Diversity Preservation International) | es_ES |
| dc.relation | PIUNA Project of the University of Navarra | - |
| dc.rights | info:eu-repo/semantics/openAccess | es_ES |
| dc.subject | Chalcone | es_ES |
| dc.subject | Quinoxaline 1,4-di-N-oxide | es_ES |
| dc.subject | Quinoxaline | es_ES |
| dc.subject | Antimalarial agents | es_ES |
| dc.subject | Plasmodium falciparum | es_ES |
| dc.title | Synthesis, biological evaluation and structure-activity relationships of new quinoxaline derivatives as anti-Plasmodium falciparum agents | es_ES |
| dc.type | info:eu-repo/semantics/article | es_ES |
| dc.identifier.doi | http://dx.doi.org/10.3390/molecules19022166 | es_ES |
Files in This Item:
Statistics and impact
Items in Dadun are protected by copyright, with all rights reserved, unless otherwise indicated.
