Full metadata record
DC Field | Value | Language |
---|---|---|
dc.creator | Arru, G. (Giannina) | - |
dc.creator | Mameli, G. (Giuseppe) | - |
dc.creator | Astone, V. (Vito) | - |
dc.creator | Serra, C. (Caterina) | - |
dc.creator | Huang, Y.M. (Yu-Min) | - |
dc.creator | Link, H. (Hans) | - |
dc.creator | Fainardi, E. (Enrico) | - |
dc.creator | Castellazzi, M. (Massimiliano) | - |
dc.creator | Granieri, E. (Enrico) | - |
dc.creator | Fernandez, M. (Miriam) | - |
dc.creator | Villoslada, P. (Pablo) | - |
dc.creator | Fois, M.L. (Maria Laura) | - |
dc.creator | Sanna, A. (Alessandra) | - |
dc.creator | Rosati, G. (Giulio) | - |
dc.creator | Dolei, A. (Antonina) | - |
dc.creator | Sotgiu, S. (Stefano) | - |
dc.date.accessioned | 2014-07-15T10:03:16Z | - |
dc.date.available | 2014-07-15T10:03:16Z | - |
dc.date.issued | 2007 | - |
dc.identifier.citation | Arru G, Mameli G, Astone V, Serra C, Huang YM, Link H, et al. Multiple sclerosis and HERV-W/MSRV: A multicentric study. Int J Biomed Sci. 2007 Dec;3(4):292-297. | es_ES |
dc.identifier.issn | 1550-9702 | - |
dc.identifier.uri | https://hdl.handle.net/10171/36159 | - |
dc.description.abstract | We designed a large multicentric study to analyse the presence of MSRV particles in blood and CSF of a large cohort of patients and controls from different European areas. 149 MS patients and 153 neurological and healthy controls were selected from Sardinia, Spain, Northern-Italy and Sweden. To avoid biological and inter-assay variability MSRV was detected within a single laboratory through nested and real-time PCR assays specific for pol and env genes. MSRV detection in blood and CSF of MS patients and controls in populations of different ethnicity gave significant differences (p<0.05 compared to neurological controls and <0.001 compared to healthy controls). The presence and viral load of MSRV are significantly associated with MS as compared to neurological and healthy controls in all ethnic groups. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Master Publishing Group | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | HERV-W | es_ES |
dc.subject | MSRV | es_ES |
dc.subject | Multiple sclerosis | es_ES |
dc.subject | Human endogenous retrovirus | es_ES |
dc.title | Multiple sclerosis and HERV-W/MSRV: A multicentric study | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
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