Modelos experimentales de enfermedad de Parkinson

Luquin, M.R. (María Rosario)

Authors:

Luquin, M.R. (María Rosario)

Keywords:

1-metil-4-fenil,1,2,3,6 tetrahidropiridina
6-hidroxidopamina
Enfermedad de Parkinson

Issue Date:

2000

Publisher:

Cesar Viguera

ISSN:

0210-0010

Citation:

Luquin MR. Modelos experimentales de enfermedad de Parkinson. Rev Neurol. 2000 Jul 1-15;31(1):60-6.

Abstract

This article reviews the most useful animal models of Parkinson's disease available. Basically they include the model of unilateral nigrostriatal lesion induced by 6-hydroxydopamine (6-OHDA) in rodents and the 1-methy-4-phenyl-1,2,3,6, tetrahydropyridine (MPTP) model of parkinsonism in non-human primates. The major neurochemical and histological alterations found in these two models are also analyzed. Finally, possible applications of these models of parkinsonism are also discussed.

URI:

https://hdl.handle.net/10171/36412

Appears in Collections:

DA - CUN - Neurología - Artículos de revista

Files in This Item: