Full metadata record
DC Field | Value | Language |
---|---|---|
dc.creator | Pinazo-Duran, M.D. (M. Dolores) | - |
dc.creator | Gomez-Ulla, F. (Francisco) | - |
dc.creator | Arias, L. (Luis) | - |
dc.creator | Araiz, J. (Javier) | - |
dc.creator | Casaroli-Marano, R. (Ricardo) | - |
dc.creator | Gallego-Pinazo, R. (Roberto) | - |
dc.creator | Garcia-Medina, J.J. (José Javier) | - |
dc.creator | Lopez-Galvez, M.I. (María Isabel) | - |
dc.creator | Manzanas, L. (Lucía) | - |
dc.creator | Salas, A. (Anna) | - |
dc.creator | Zapata, M. (Miguel) | - |
dc.creator | Diaz-Llopis, M. (Manuel) | - |
dc.creator | Garcia-Layana, A. (Alfredo) | - |
dc.date.accessioned | 2014-09-15T10:26:06Z | - |
dc.date.available | 2014-09-15T10:26:06Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Pinazo-Durán MD, Gómez-Ulla F, Arias L, Araiz J, Casaroli-Marano R, Gallego-Pinazo R, et al. Do nutritional supplements have a role in age macular degeneration prevention?. J Ophthalmol. 2014;2014:901686. | es_ES |
dc.identifier.issn | 2090-004X | - |
dc.identifier.uri | https://hdl.handle.net/10171/36562 | - |
dc.description.abstract | Purpose. To review the proposed pathogenic mechanisms of age macular degeneration (AMD), as well as the role of antioxidants (AOX) and omega-3 fatty acids ( ω -3) supplements in AMD prevention. Materials and Methods. Current knowledge on the cellular/molecular mechanisms of AMD and the epidemiologic/experimental studies on the effects of AOX and ω -3 were addressed all together with the scientific evidence and the personal opinion of professionals involved in the Retina Group of the OFTARED (Spain). Results. High dietary intakes of ω -3 and macular pigments lutein/zeaxanthin are associated with lower risk of prevalence and incidence in AMD. The Age-Related Eye Disease study (AREDS) showed a beneficial effect of high doses of vitamins C, E, beta-carotene, and zinc/copper in reducing the rate of progression to advanced AMD in patients with intermediate AMD or with one-sided late AMD. The AREDS-2 study has shown that lutein and zeaxanthin may substitute beta-carotene because of its potential relationship with increased lung cancer incidence. Conclusion. Research has proved that elder people with poor diets, especially with low AOX and ω -3 micronutrients intake and subsequently having low plasmatic levels, are more prone to developing AMD. Micronutrient supplementation enhances antioxidant defense and healthy eyes and might prevent/retard/modify AMD. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Hindawi Publishing Corporation | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Age macular degeneration (AMD) | es_ES |
dc.subject | Antioxidants | es_ES |
dc.subject | Omega-3 fatty acids | es_ES |
dc.subject | Prevention | es_ES |
dc.title | Do nutritional supplements have a role in age macular degeneration prevention? | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.identifier.doi | http://dx.doi.org/10.1155/2014/901686 | es_ES |
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