Alprostadil/pharmacology Cardioplegic Solutions Heart Transplantation Organ Preservation/methods Perfusion/methods
Herreros J, Abaya AR, Ponz L, Gil JM, Llorens R, Errasti P, et al. Experimental heart preservation for 24 hours: benefits of PGE1 in a nonpulsatile coronary perfusion solution. Transplant Proc. 1988 Oct;20(5):1033-4.
The increase in activity of centers with cardiac transplant programs has been limited
because of the unavailability of high quality donor organs. Nonpulsatile coronary
perfusion (NPCP) with hypothermia has allowed long-term cardiac preservation in
various experimental models.1-4 This experiment was designed to study the effects of PGE1 in an experimental NPCP.