Metal-Organic Frameworks for Drug Delivery Applications
Palabras clave : 
Materias Investigacion::Ciencias de la vida
Preparación de fármacos
Análisis de fármacos
Composición de fármacos
Evaluación de fármacos
Fecha de publicación: 
2014
Fecha de la defensa: 
25-jul-2014
Cita: 
TAMAMES TABAR, Cristina. “Metal-Organic Frameworks for Drug Delivery Applications”. Blanco Prieto, María José y Horcajada, Patricia (dir.). Tesis doctoral. Universidad de Navarra, Pamplona, 2014
Resumen
In this work, a new type of particles denoted as MOFs or Metal-Organic Frameworks, have been studied as a new drug carriers. First, they were synthesised at the nanoscale (NPs) using, when possible, biofriendly methods. Their cytotoxicity, as well as that from their constitutive linkers, was evaluated by the MTT test in murine macrophage (J774) and in cervix carcinoma (HeLa) cell lines, observing: (i) a low cytotoxicity of MOFs, comparable with other described particulated systems, (ii) a strong influence of the composition (toxicity order: Fe

Ficheros en este registro:
Fichero: 
Cristina Tamames Tabar.pdf
Descripción: 
Tamaño: 
16,66 MB
Formato: 
Adobe PDF


Los ítems de Dadun están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.