Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | Troconiz, I.F. (Iñaki F.) | - |
| dc.creator | García-Cremades, M. (María) | - |
| dc.date.accessioned | 2017-11-16T12:11:44Z | - |
| dc.date.available | 2017-11-16T12:11:44Z | - |
| dc.date.issued | 2017-11-14 | - |
| dc.date.submitted | 2017-09-29 | - |
| dc.identifier.citation | GARGÍA-CREMADES, María. “Pharmacokinetic/Pharmacodynamic Modelling-Based Translational Approach applied to the Anticancer Drug Gemcitabine in Advanced Pancreatic and Ovarian Cancer”. Fernández de Trocóniz, J.I. (dir.). Tesis doctoral. Universidad de Navarra, Pamplona, 2017. | es_ES |
| dc.identifier.uri | https://hdl.handle.net/10171/44870 | - |
| dc.description.abstract | This thesis performs a retrospective evaluation of data generated for the cytotoxic/cytostatic antimetabolite drug gemcitabine along the different phases of drug development. Using these data, and through data analysis and simulations-based translational exercise, a model-based framework in oncology, relating in vitro and in vivo pre-clinical pharmacokinetic (PK) and tumour size (TS) information, with response outcome obtained in clinical trials, has been developed. | es_ES |
| dc.language.iso | eng | es_ES |
| dc.rights | info:eu-repo/semantics/openAccess | es_ES |
| dc.subject | Materias Investigacion::Farmacia::Farmacia y farmacología | es_ES |
| dc.subject | Pharmacometrics | es_ES |
| dc.title | Pharmacokinetic/Pharmacodynamic Modelling-Based Translational Approach applied to the Anticancer Drug Gemcitabine in Advanced Pancreatic and Ovarian Cancer | es_ES |
| dc.type | info:eu-repo/semantics/doctoralThesis | es_ES |
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