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dc.creatorSanchez-Villegas, A. (Almudena)-
dc.creatorAlvarez Perez, J. (Jacqueline)-
dc.creatorToledo, E. (Estefanía)-
dc.creatorSalas-Salvado, J. (Jordi)-
dc.creatorOrtega-Azorin, C. (Carolina)-
dc.creatorZomeño, M.D. (María Dolores)-
dc.creatorVioque, J. (Jesús)-
dc.creatorMartinez, J.A. (José Alfredo)-
dc.creatorRomaguera, D. (Dora)-
dc.creatorPérez-Lopez, J. (Jessica)-
dc.creatorLópez-Miranda, J. (José)-
dc.creatorEstruch, R. (Ramón)-
dc.creatorBueno-Cavanillas, A. (Aurora)-
dc.creatorAros, F. (Fernando)-
dc.creatorTur, J.A. (Josep A.)-
dc.creatorTinahones, F.J. (Francisco J.)-
dc.creatorLecea, O. (Oscar)-
dc.creatorMartin, V. (Vicente)-
dc.creatorOrtega-Calvo, M. (Manuel)-
dc.creatorVázquez, C. (Clotilde)-
dc.creatorPinto, X. (Xavier)-
dc.creatorVidal, J. (Josep)-
dc.creatorDaimiel, L (Lidia)-
dc.creatorDelgado-Rodriguez, M. (Miguel)-
dc.creatorMatia, P. (Pilar)-
dc.creatorCorella, D. (Dolores)-
dc.creatorDiaz-Lopez, A. (Andres)-
dc.creatorBabio, N. (Nancy)-
dc.creatorMuñoz, M.A. (Miguel Angel)-
dc.creatorFito, M. (Montserrat)-
dc.creatorGarcía Hera, M (Manoli) de la-
dc.creatorAbete, I. (Itziar)-
dc.creatorGarcia-Rios, A. (Antonio)-
dc.creatorRos, E. (Emilio)-
dc.creatorRuiz-Canela, M. (Miguel)-
dc.creatorMartinez-Gonzalez, M.A. (Miguel Ángel)-
dc.creatorIzquierdo, M. (Marisol)-
dc.creatorSerra-Majem, L. (Lluis)-
dc.date.accessioned2019-03-21T12:49:26Z-
dc.date.available2019-03-21T12:49:26Z-
dc.date.issued2018-12-18-
dc.identifier.citationSanchez-Villegas, A. (Almudena); Alvarez Perez, J. (Jacqueline); Toledo, E. (Estefanía); et al. "Seafood Consumption, Omega-3 Fatty Acids Intake, and Life-Time Prevalence of Depression in the PREDIMED-Plus Trial". Nutrients. vol.10, 2018-12-18,es_ES
dc.identifier.issn2072-6643-
dc.identifier.urihttp://hdl.handle.net/10171/56649-
dc.description.abstractBackground: The aim of this analysis was to ascertain the type of relationship between fish and seafood consumption, omega-3 polyunsaturated fatty acids (ω-3 PUFA) intake, and depression prevalence. Methods: Cross-sectional analyses of the PREDIMED-Plus trial. Fish and seafood consumption and ω-3 PUFA intake were assessed through a validated food-frequency questionnaire. Self-reported life-time medical diagnosis of depression or use of antidepressants was considered as outcome. Depressive symptoms were collected by the Beck Depression Inventory-II. Logistic regression models were used to estimate the association between seafood products and ω-3 PUFA consumption and depression. Multiple linear regression models were fitted to assess the association between fish and long-chain (LC) ω-3 PUFA intake and depressive symptoms. Results: Out of 6587 participants, there were 1367 cases of depression. Total seafood consumption was not associated with depression. The odds ratios (ORs) (95% confidence intervals (CIs)) for the 2nd, 3rd, and 4th quintiles of consumption of fatty fish were 0.77 (0.63–0.94), 0.71 (0.58–0.87), and 0.78 (0.64–0.96), respectively, and p for trend = 0.759. Moderate intake of total LC ω-3 PUFA (approximately 0.5–1 g/day) was significantly associated with a lower prevalence of depression. Conclusion: In our study, moderate fish and LC ω-3 PUFA intake, but not high intake, was associated with lower odds of depression suggesting a U-shaped relationship.es_ES
dc.description.sponsorshipThis research was funded by the Spanish Ministry of Health (Carlos III Health Institute) through the Fondo de Investigación para la Salud (FIS), which is co-funded by the European Regional Development Fund (grant numbers and corresponding codes: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14-00696, PI14/01206, PI14/01919, PI14/00853), the European Research Council (Advanced Research Grant 2013–2018; 340918) grant to MAMG, the Recercaixa grant to J. S-S. and NB (2013ACUP00194), the grant from the Consejería de Salud de la Junta de Andalucía (PI0458/2013; PS0358/2016), the SEMERGEN grant, and FEDER funds (CB06/03).es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectFishes_ES
dc.subjectOmega-3es_ES
dc.subjectEicosapentaenoic acides_ES
dc.subjectDocosahexaenoic acides_ES
dc.subjectDepressiones_ES
dc.titleSeafood Consumption, Omega-3 Fatty Acids Intake, and Life-Time Prevalence of Depression in the PREDIMED-Plus Triales_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttps://doi.org/10.3390/nu10122000es_ES
dc.description.noteThis article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) licensees_ES
dc.identifier.doihttps://doi.org/10.3390/nu10122000-

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