Glucocerebrosidase gene therapy in animal models of Parkinson Disease

Abstract

Parkinson´s Disease (PD) is the first most common movement disorder and second most common neurodegenerative disease that affects 1.5% of the global population above 65 years old. Although the incidence of PD varies depending on genetic, race/ethnicity and environmental factors, advanced age has been appointed as the main risk factor for PD.