Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Aragón-Aranda, B. (Beatriz) | - |
| dc.creator | Miguel, M.J. (María Jesús) de | - |
| dc.creator | Martinez-Gomez, E. (Estrella) | - |
| dc.creator | Zuñiga-Ripa, A. (Amaia) | - |
| dc.creator | Salvador-Bescós, M. (Miriam) | - |
| dc.creator | Moriyon, I. (Ignacio) | - |
| dc.creator | Muñoz, P. (Pilar) | - |
| dc.creator | Raquel | - |
| dc.date.accessioned | 2021-08-24T06:13:27Z | - |
| dc.date.available | 2021-08-24T06:13:27Z | - |
| dc.date.issued | 2019 | - |
| dc.identifier.citation | Aragón-Aranda, B. (Beatriz); Miguel, M.J. (María Jesús) de; Martinez-Gomez, E. (Estrella); et al. "Rev1 wbdR tagged vaccines against Brucella ovis". Veterinary Research. 50 (95), 2019, 1 - 9 | es_ES |
| dc.identifier.issn | 0928-4249 | - |
| dc.identifier.other | PMID: 31730501 | - |
| dc.identifier.uri | https://hdl.handle.net/10171/61550 | - |
| dc.description.abstract | Sheep brucellosis is a worldwide extended disease caused by B. melitensis and B. ovis, two species respectively carrying smooth or rough lipopolysaccharide. Vaccine B. melitensis Rev1 is used against B. melitensis and B. ovis but induces an anti-smooth-lipopolysaccharide response interfering with B. melitensis serodiagnosis, which precludes its use against B. ovis where B. melitensis is absent. In mice, Rev1 deleted in wbkC (Brucella lipopolysaccharide formyltransferase) and carrying wbdR (E. coli acetyl-transferase) triggered antibodies that could be diferentiated from those evoked by wild-type strains, was comparatively attenuated and protected against B. ovis, suggesting its potential as a B. ovis vaccine. | es_ES |
| dc.description.sponsorship | This research was supported by the Institute for Tropical Health funders (Obra Social la CAIXA-LCF/PR/PR13/11080005- and Fundación Caja Navarra, Fundación María Francisca de Roviralta, Ubesol and Inversiones Garcilaso de la Vega S.L.) and grants MINECO (AGL2014-58795-C4-1-R). B.A.A. is the recipient of the Ph.D. Fellowship BES-2015-075609 funded by the MINECO. | es_ES |
| dc.language.iso | eng | es_ES |
| dc.publisher | Springer Science and Business Media LLC | es_ES |
| dc.rights | info:eu-repo/semantics/openAccess | es_ES |
| dc.subject | Materias Investigacion::Ciencias de la vida::Inmunología | es_ES |
| dc.title | Rev1 wbdR tagged vaccines against Brucella ovis | es_ES |
| dc.type | info:eu-repo/semantics/article | es_ES |
| dc.description.note | This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | es_ES |
| dc.identifier.doi | 10.1186/s13567-019-0714-3 | - |
| dadun.citation.endingPage | 9 | es_ES |
| dadun.citation.number | 95 | es_ES |
| dadun.citation.publicationName | Veterinary Research | es_ES |
| dadun.citation.startingPage | 1 | es_ES |
| dadun.citation.volume | 50 | es_ES |
Ficheros en este ítem:
Estadísticas e impacto
Los ítems de Dadun están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.
