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Campo DC | Valor | Lengua/Idioma |
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dc.creator | Dominguez, L.J. (Ligia J.) | - |
dc.creator | Gea, A. (Alfredo) | - |
dc.creator | Ruiz-Estigarribia, L. (Liz) | - |
dc.creator | Sayon-Orea, C. (Carmen) | - |
dc.creator | Fresan, U. (Ujue) | - |
dc.creator | Barbagallo, M. (Mario) | - |
dc.creator | Ruiz-Canela, M. (Miguel) | - |
dc.creator | Martinez-Gonzalez, M.A. (Miguel Ángel) | - |
dc.date.accessioned | 2022-02-22T07:07:54Z | - |
dc.date.available | 2022-02-22T07:07:54Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Dominguez, L. J.; Gea-Sánchez, A. (Alfredo); Ruiz-Estigarribia, L. (Liz María); et al. "Low dietary magnesium and overweight/obesity in a Mediterranean population: a detrimental synergy for the development of hypertension. The SUN Project". Nutrients. 13 (1), 2021, 125 | es |
dc.identifier.issn | 2072-6643 | - |
dc.identifier.uri | https://hdl.handle.net/10171/62947 | - |
dc.description.abstract | Hypertension is the strongest independent modifiable risk factor for cardiovascular disease. We aimed to investigate the association of magnesium intake with incident hypertension in a Mediterranean population, and the potential modification of this association by body mass index (BMI). We assessed 14,057 participants of the SUN (Seguimiento Universidad de Navarra) prospective cohort (67.0% women) initially free of hypertension. At baseline, a validated 136-item food frequency questionnaire was administered. We used Cox models adjusted for multiple socio-demographic, anthropometric, and lifestyle factors, and prevalent conditions present at baseline. Among a mean 9.6 years of follow-up we observed 1406 incident cases of medically diagnosed hypertension. An inverse association in multivariable-adjusted models was observed for progressively higher magnesium intake up to 500 mg/d vs. intake < 200 mg/d, which was greater among those with a BMI > 27 kg/m(2). Lean participants with magnesium intake < 200 mg/d vs. >200 mg/d also had a higher risk of incident hypertension. Adherence to the Mediterranean diet did not modify these associations. In conclusion, dietary magnesium intake < 200 mg/d was independently associated with a higher risk of developing hypertension in a Mediterranean cohort, stronger for overweight/obese participants. Our results emphasize the importance of encouraging the consumption of magnesium-rich foods (vegetables, nuts, whole cereals, legumes) in order to prevent hypertension. | - |
dc.description.sponsorship | The SUN Project has received funding from the Spanish Government-Instituto de Salud Carlos III, and the European Regional Development Fund (FEDER) (RD 06/0045), CIBER-OBN, Grants PI10/02658, PI10/02293, PI13/00615, PI14/01668, PI14/01798, PI14/01764, and PI17/01795. | - |
dc.language.iso | en | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | Magnesium | - |
dc.subject | Hypertension | - |
dc.subject | Obesity | - |
dc.subject | Overweight | - |
dc.subject | Diet | - |
dc.subject | Cohort studies | - |
dc.title | Low dietary magnesium and overweight/obesity in a Mediterranean population: a detrimental synergy for the development of hypertension. The SUN Project | - |
dc.type | info:eu-repo/semantics/article | - |
dc.description.note | This article is an open access article distributed under the terms and con- ditions of the Creative Commons At- tribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/) | - |
dc.identifier.doi | 10.3390/nu13010125 | - |
dadun.citation.number | 1 | - |
dadun.citation.publicationName | Nutrients | - |
dadun.citation.startingPage | 125 | - |
dadun.citation.volume | 13 | - |
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