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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.creator | Banaschewski, T. (Tobias) | - |
dc.creator | Johnson, M. (Mats) | - |
dc.creator | Nagy, P. (Peter) | - |
dc.creator | Hernández-Otero, I. (Isabel) | - |
dc.creator | Soutullo-Esperón, C. (César Alejandro) | - |
dc.creator | Yan, B. (Brian) | - |
dc.creator | Zuddas, A. (Alessandro) | - |
dc.creator | Coghill, D. (David) | - |
dc.date.accessioned | 2022-11-08T11:01:11Z | - |
dc.date.available | 2022-11-08T11:01:11Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Banaschewski, T. (Tobias); Johnson, M. (Mats); Nagy, P. (Peter); et al. "Growth and puberty in a 2-year open-label study of lisdexamfetamine dimesylate in children and adolescents with attention-deficit/hyperactivity disorder". Cns drugs. 32 (5), 2018, 455 - 467 | es_ES |
dc.identifier.issn | 1172-7047 | - |
dc.identifier.uri | https://hdl.handle.net/10171/64612 | - |
dc.description.abstract | Background: Stimulant medications for the treatment of attention-deficit/hyperactivity disorder have a history of safe and effective use; however, concerns exist that they may adversely affect growth trajectories in children and adolescents. Objective: The objective of this study was to evaluate the longer-term effects of lisdexamfetamine dimesylate on weight, height, body mass index and pubertal development in children and adolescents with attention-deficit/hyperactivity disorder. Methods: Children and adolescents aged 6–17 years with attention-deficit/hyperactivity disorder took open-label lisdexamfetamine dimesylate (30, 50 or 70 mg/day) in this open-label 2-year safety and efficacy study. Safety evaluations included treatment-emergent adverse events, measurement of weight, height and body mass index, and selfreported pubertal status using Tanner staging. Results: The safety analysis population comprised all enrolled participants (N = 314) and 191 (60.8%) completed the study. Weight decrease was reported as a treatmentemergent adverse event in 63 participants (20.1%) and two participants (0.6%) discontinued the study as a result of treatment-emergent adverse events of weight decrease. | es_ES |
dc.description.sponsorship | This study was funded by Shire Development LLC. Writing and editing assistance for this paper was provided by Oxford PharmaGenesis, funded by Shire International GmbH. Shire International GmbH also funded open access. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Springer | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Stimulant medications | es_ES |
dc.subject | Treatment of attention-deficit/hyperactivity disorder | es_ES |
dc.subject | Growth trajectories | es_ES |
dc.subject | Children | es_ES |
dc.subject | Adolescents | es_ES |
dc.title | Growth and puberty in a 2-year open-label study of lisdexamfetamine dimesylate in children and adolescents with attention-deficit/hyperactivity disorder | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.description.note | This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. | es_ES |
dc.identifier.doi | 10.1007/s40263-018-0514-8 | - |
dadun.citation.endingPage | 467 | es_ES |
dadun.citation.number | 5 | es_ES |
dadun.citation.publicationName | Cns drugs | es_ES |
dadun.citation.startingPage | 455 | es_ES |
dadun.citation.volume | 32 | es_ES |
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