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Validity of a self-reported diagnosis of depression among participants in a cohort study using the Structured Clinical Interview for DSM-IV (SCID-I).
Authors: Sanchez-Villegas, A. (Almudena)
Schlatter, J. (Javier)
Ortuño-Sánchez-Pedreño, F. (Felipe)
Lahortiga, F. (Francisca)
Pla, J. (Jorge)
Benito-Corchon, S. (Silvia)
Martinez-Gonzalez, M.A. (Miguel Ángel)
Keywords: Materias Investigacion::Ciencias de la Salud::Psiquiatría y psicología
Materias Investigacion::Ciencias de la Salud::Medicina preventiva
Issue Date: 2008
Publisher: Biomed Central
ISSN: 1471-244x
Citation: BMC Psychiatry 2008 17;8 (43).
Abstract Background: Depression assessment in population studies is usually based on depressive symptoms scales. However, the use of scales could lead to the choice of an arbitrary cut-off point depending on the sample characteristics and on the patient diagnosis. Thus, the use of a medical diagnosis of depression could be a more appropriate approach. Objective: To validate a self-reported physician diagnosis of depression using the Structured Clinical Interview for DSM-IV (SCID-I) as Gold Standard and to assess the factors associated to a valid self-reported diagnosis. Methods: The SUN Project is a cohort study based on university graduates followed-up through postal questionnaires. The response to the question included in the questionnaire: Have you ever been diagnosed of depression by a physician? was compared to that obtained through the SCID-I applied by a psychiatrist or a clinical psychologist. The percentages of confirmed depression and non-depression were assessed for the overall sample and according to several characteristics. Logistic regression models were fitted to ascertain the association between different factors and a correct classification regarding depression status. Results: The percentage of confirmed depression was 74.2%; 95% confidence interval (95% CI) =63.3-85.1. Out of 42 participants who did not report a depression diagnosis in the questionnaire, 34 were free of the disease (%confirmed non-depression=81.1%; 95% CI=69.1- 92.9). The probability of being a true positive was higher among ex- smokers and non-smokers and among those overweight or obese but the differences were not statistically significant. Conclusion: The validity of a self-reported diagnosis of depression in the SUN cohort is adequate. Thus, this question about depression diagnosis could be used in further investigations regarding this disease in this graduate cohort study.
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