Martinez-Caro, D. (Diego)
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- Falso aneurisma aórtico 30 años después de la corrección de una coartación: tratamiento quirúrgico bajo hipotermia profunda(Ediciones Universidad de Navarra, 2014) Lopez-Coronado, J.L. (José Luis); Saenz-de-Buruaga, J.D. (J. D.); Martinez-Caro, D. (Diego); Martin-Trenor, A. (Alejandro)We report a case of a large false aortic aneurysm that had developed in a 43-year-old man who had had coarctation repair 30 years previously. The coarctation repair had been done by inserting an end-to-end Dacron tubular graft which was sutured with silk. The re-operation was successfully performed under deep hypothermic arrest and it was noted that there was complete separation of the graft from both ends and no sutures were visualised. The deep hypothermic technique has considerably improved the ease and safety of this operation. We attribute this complication to the reabsorption of the silk sutures. Patients after coarctectomy with graft material should have regular chest X-rays for life in order to detect false aneurysm
- Repeated implantation of skeletal myoblast in a swine model of chronic myocardial infarction(Oxford University Press, 2010) Nasarre, E. (Emilio); Gavira, J.J. (Juan José); Perez-Ilzarbe, M. (Maitane); Macias, A. (Alfonso); Mazo, M. (Manuel); Martinez-Caro, D. (Diego); Garcia-Bolao, I. (Ignacio); Martino-Rodriguez, A. (Alba) de; Garcia-de-Jalon, J.A. (José A.); Prosper-Cardoso, F. (Felipe); Pelacho, B. (Beatriz); Abizanda-Sarasa, G. (Gloria)Although transplantation of skeletal myoblast (SkM) in models of chronic myocardial infarction (MI) induces an improvement in cardiac function, the limited engraftment remains a major limitation. We analyse in a pre-clinical model whether the sequential transplantation of autologous SkM by percutaneous delivery was associated with increased cell engraftment and functional benefit.
- Receptores beta e isquemia miocárdica(Gobierno de Navarra, Departamento de Salud, 1997) Herreros, J. (Jesús); Gil, O. (O.); Iglesias, I. (I.); Diaz, C. (C.); Alegria, E. (Eduardo); Barba, J. (Joaquín); Martinez-Caro, D. (Diego); Garcia-Bolao, I. (Ignacio)
- Vitamins C and E attenuate plasminogen activator inhibitor-1 (PAI-1) expression in a hypercholesterolemic porcine model of angioplasty(Oxford University Press, 2001) Belzunce, M. (Miriam); Paramo, J.A. (José Antonio); Orbe, J. (Josune); Rodriguez, J.A. (José Antonio); Grau, A. (Andrés); Martinez-Caro, D. (Diego); Calvo-González, A. (Alfonso)BACKGROUND: The plasminogen activator inhibitor-1 (PAI-1), which modulates fibrinolysis and cell migration, may influence proteolysis and neointimal formation in the arterial wall contributing to restenosis after vascular injury. Antioxidants have been proposed as inhibiting multiple proatherogenic events. We explore the effect of vitamins C and E on PAI-1 expression in an experimental model of angioplasty in hypercholesterolemic pigs. METHODS AND RESULTS: A total of 44 Yucatan minipigs were divided into three diet groups: a normal-cholesterol (NC), a high-cholesterol (HC), and a high-cholesterol plus vitamins C+E (HCV) group. Balloon injury was induced in the right internal iliac artery 4 weeks after initiation of either dietary regimen, and plasma and tissue samples were taken at different time periods to measure PAI-1 activity and vascular inhibitor expression. The cholesterol-rich diet induced an increased in vascular PAI-1 expression in the intima, media and adventitia which was markedly reduced in the HCV group. After injury, severe structural changes were observed in NC and HC animals associated with increased systemic PAI-1 activity (P<0.001) and local PAI-1 expression being more intense in HC group. Vitamins C and E significantly reduced plasma PAI-1 activity (P=0.018) and attenuated the inhibitor expression as compared with HC. CONCLUSIONS: This experimental study in a porcine model of hypercholesterolemia demonstrates that vitamins C and E reduce local and systemic PAI-1 induced after angioplasty as well as the hypercholesterolemia-induced vascular PAI-1.
- [San Luis Bertrán] [Material gráfico]([Valencia : Lit. P. Marti-Editor- C. Miguelete,9, 2012-11-30) Martinez-Caro, D. (Diego); Martí Casanova, Pedro
- [San Luis Bertrán] [Material gráfico] / P. Marti litografio([Alcoy : Lit. de J. Marti y Roij, 2012-11-30) Martinez-Caro, D. (Diego); Martí Casanova, Pedro
- A comparison between percutaneous and surgical transplantation of autologous skeletal myoblasts in a swine model of chronic myocardial infarction(Oxford University Press, 2006) Belzunce, M. (Miriam); Herreros, J. (Jesús); Paramo, J.A. (José Antonio); Gavira, J.J. (Juan José); Orbe, J. (Josune); Perez-Ilzarbe, M. (Maitane); Barba, J. (Joaquín); Rabago, G. (Gregorio); Panizo, A. (Ángel); Martinez-Caro, D. (Diego); Garcia-Rodriguez, A. (Alba); Garcia-de-Jalon, J.A. (José A.); Prosper-Cardoso, F. (Felipe); Abizanda-Sarasa, G. (Gloria)
- ¡Santificado sea el dolor! Aspectos médicos de la biografía del Beato Josemaría Escrivá de Balaguer(Servicio de Publicaciones de la Universidad de Navarra, 2002) Martinez-Caro, D. (Diego); Cantero-Fariña, A. (Alejandro)
- [San Francisco de Asís] [Material gráfico] / Pedro Marti litografió ; Fran.co Manno inv. y pin.([Alcoy : A expensas de su Tercera Orden, Lit. de J. Marti Roig), 2012-11-30) Manno, Francisco; Martinez-Caro, D. (Diego); Martí Casanova, Pedro
- Vista de la ciudad de Valencia por la parte de Quarte [Material gráfico](Alcoy : Imp. y Lib. de José Martí, 2012-11-30) Martinez-Caro, D. (Diego)