Ruiz-de-Azúa, Y. (Yerani)

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    A bilateral whitish lesion on the mucosa of the cheek
    (Elsevier, 2022) Bronte-Anaut, M. (Mónica); Fernández-Seara, M.P. (María del Pilar); Guarch-Troyas, R. (Rosa); Arredondo-Montero, J. (Javier); Antona, G. (Giuseppa); Ruiz-de-Azúa, Y. (Yerani); Peñafiel-Freire, D.M. (Diego Mauricio)
    An 8-year-old girl with no medical history presented with a bilateral whitish lesion on the mucosa of the cheek, evident since early childhood. There was no relevant family history, and her parents had not presented similar lesions. They reported a progressive growth of the lesion in the last months, for which she had been evaluated by maxillofacial surgery, the lesion being oriented as a frictional keratosis. However, the use of occlusal splint was not associated with any improvement. She was otherwise asymptomatic. Physical examination revealed a bilateral, whitish, well-demarcated cheek mucosal plaque, which partially coincided with the dental occlusion line. The lesion did not detach with scratching (Figure 1). No other alterations were observed in the oral cavity or in the systematic physical examination.
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    Unilateral galactocele in a 2-year-old boy: the role of GATA-3
    (Springer, 2023) Bronte-Anaut, M. (Mónica); Arredondo-Montero, J. (Javier); Hernández-Martín, S. (Sara); Ayuso-González, L. (Lidia); Ruiz-de-Azúa, Y. (Yerani)
    Galactoceles are benign lesions formed at the expense of breast glandular tissue. Its occurrence in boys is exceptional, with isolated reports in the scientifc literature. We present the case of a 2-year-old boy who debuted with a unilateral breast enlargement of 18 months of evolution, with no other associated symptoms. Initial hormonal study showed no alterations. Ultrasonography showed the presence of a homogeneous 5-cm retroareolar cyst. Surgical excision was indicated. During the procedure, abundant milk drained from the lesion. The histopathological study, supported by GATA-3 immunohistochemical staining, confrmed the diagnosis of galactocele. The range of possible diferential diagnoses for unilateral or bilateral breast enlargement in boys is wide and includes neoplastic, vascular, and hormonal etiologies. Galactocele, which is an exceptional entity in this group, should be considered. Immunohistochemical techniques such as GATA-3, characteristic of the breast epithelium, can contribute to the diagnosis.