Fabra, S. (Sofia)

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    Diagnostic performance of two-dimensional ultrasound, two-dimensional sonohysterography and three-dimensional ultrasound in the diagnosis of septate uterus-a systematic review and meta-analysis
    (2023) Aguilar, M.I. (María Isabel); Castellet, C. (Cristina); Oliva, A. (Agustín); Alcazar, J.L. (Juan Luis); Guerriero, S. (Stefano); Monroy, A. (Alba); Cajas, M.B. (María Belén); Cabrero, M. (María); Laza, M.V. (María Victoria); Tomaizeh, A. (Aida); Fabra, S. (Sofia); Castro, E. (Elena); Carriles-Rivero, I.M. (Isabel María); Martínez, I. (Irene); Pascual, M.A. (Maria Angela); Hernani, E. (Elena)
    Background: The septate uterus is the most common congenital uterine anomaly, and hysteroscopy is the gold standard for diagnosing it. The goal of this meta-analysis is to perform a pooled analysis of the diagnostic performance of two-dimensional transvaginal ultrasonography, two-dimensional transvaginal sonohysterography, three-dimensional transvaginal ultrasound, and three-dimensional transvaginal sonohysterography for the diagnosis of the septate uterus. Methods: Studies published between 1990 and 2022 were searched in PubMed, Scopus, and Web of Science. From 897 citations, we selected eighteen studies to include in this meta-analysis. Results: The mean prevalence of uterine septum in this meta-analysis was 27.8%. Pooled sensitivity and specificity were 83% and 99% for two-dimensional transvaginal ultrasonography (ten studies), 94% and 100% for two-dimensional transvaginal sonohysterography (eight studies), and 98% and 100% for three-dimensional transvaginal ultrasound (seven articles), respectively. The diagnostic accuracy of three-dimensional transvaginal sonohysterography was only described in two studies, and we did not calculate the pooled sensitivity and specificity for this method. Conclusion: Three-dimensional transvaginal ultrasound has the best performance capacity for the diagnosis of the septate uterus.