Kellman, P. (Peter)

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    Reverse myocardial remodeling following valve replacement in patients with aortic stenosis
    (Elsevier BV, 2018) Manisty, C. (Charlotte); Schofield, R.S. (Rebecca S.); Bhuva, A.N. (Anish N.); Treibel, T.A. (Thomas A.); Sheikh, A. (Amir); Benedetti, G. (Giulia); Moon, J.C. (James C.); Gonzalez, A. (Arantxa); Lloyd, G. (Guy); Kellman, P. (Peter); Kozor, R. (Rebecca); López, B. (Begoña); Diez, J. (Javier); Fontana, M. (Marianna)
    Background Left ventricular (LV) hypertrophy, a key process in human cardiac disease, results from cellular (hypertrophy) and extracellular matrix expansion (interstitial fibrosis). Objectives This study sought to investigate whether human myocardial interstitial fibrosis in aortic stenosis (AS) is plastic and can regress.