Kaneko, H. (Hironori)

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    An international retrospective observational study of liver functional deterioration after repeat liver resection for patients with hepatocellular carcinoma
    (2022) Otsuka, Y. (Yuichiro); Buell, J.F. (Joseph F.); Dagher, I. (Ibrahim); Briceño, J. (Javier); Ohmura, Y. (Yoshiaki); Wilson, G.C. (Gregory C.); Wakabayashi, G. (Go); Morise, Z. (Zenichi); Rotellar, F. (Fernando); Seyama, Y. (Yasuji); Okamura, Y. (Yukiyasu); Alzoubi, M. (Mohammad); Belli, A. (Andrea); Ueno, M. (Masaki); Fuks, D. (David); Gayet, B. (Brice); Monden, K. (Kazuteru); Kawamoto, K. (Kazuyuki); Kaizu, T. (Takashi); Troisi, R.I. (Roberto I.); Kumamoto, Y. (Yusuke); Lewin, J. (Joel); Laurent, A. (Alexis); Lin, C.C.W. (Charles Chung-Wei); Cheung, T.T. (Tan To); Yasunaga, M. (Masafumi); Cherqui, D. (Daniel); Edwin, B. (Bjorn); Kato, Y. (Yutaro); Tanabe, M. (Minoru); Ome, Y. (Yusuke); Belli, G. (Giulio); Ciria-Bru, R. (Rubén); Suh, K.S. (Kyung Suk); O’Rourke, N. (Nicholas); Tanaka, S. (Shogo); Chen, K. (KuoHsin); Abu-Hilal, M. (Mohammed); Kaneko, H. (Hironori); Hashida, K. (Kazuki); Yoh, T. (Tomoaki); Shinoda, M. (Masahiro); Ekmekcigil, E. (Ela); Cho, H.D. (Hwui-Dong); Halim, N.A. (Nasser Abdul); Aldrighetti, L. (Luca); Kubo, S. (Shoji); Sadamori, H. (Hiroshi); Gotohda, N. (Naoto); Soubrane, O. (Olivier); Abe, Y. (Yuta); Lo, C.M. (Chung Mau); Geller, D.A. (David A.); Han, H.S. (Ho-Seong); Kanazawa, A. (Akishige); Ogura, T. (Toshiro); Kim, K.H. (Ki Hun); Ratti, F. (Francesca); Nitta, H. (Hiroyuki); Takeda, Y. (Yutaka); Berardi, G. (Giammauro); Sugioka, A. (Atsushi); Uesaka, K. (Katsuhiko)
    Simple Summary For 657 cases of segment or less repeat liver resection with results of plasma albumin and bilirubin levels and platelet counts before and 3 months after surgery, the indicators were compared before and after surgery. There were 268 open repeat after open and 224 cases laparoscopic repeat after laparoscopic liver resection. The background factors and liver functional indicators before and after surgery, and the changes were compared between both groups. Plasma levels of albumin (p = 0.006) and total bilirubin (p = 0.01) were decreased, and ALBI score (p = 0.001) indicated worse liver function after surgery. Though laparoscopic group had poorer performance status and liver function, changes of the values and overall survivals were similar between both groups. Plasma levels of albumin and bilirubin and ALBI score could be the liver functional indicators for liver functional deterioration after liver resection. The laparoscopic group with poorer conditions showed a similar deterioration of liver function and overall survival to the open group. Whether albumin and bilirubin levels, platelet counts, ALBI, and ALPlat scores could be useful for the assessment of permanent liver functional deterioration after repeat liver resection was examined, and the deterioration after laparoscopic procedure was evaluated. For 657 patients with liver resection of segment or less in whom results of plasma albumin and bilirubin levels and platelet counts before and 3 months after surgery could be retrieved, liver functional indicators were compared before and after surgery. There were 268 patients who underwent open repeat after previous open liver resection, and 224 patients who underwent laparoscopic repeat after laparoscopic liver resection. The background factors, liver functional indicators before and after surgery and their changes were compared between both groups. Plasma levels of albumin (p = 0.006) and total bilirubin (p = 0.01) were decreased, and ALBI score (p = 0.001) indicated worse liver function after surgery. Laparoscopic group had poorer preoperative performance status and liver function. Changes of liver functional values before and after surgery and overall survivals were similar between laparoscopic and open groups. Plasma levels of albumin and bilirubin and ALBI score could be the indicators for permanent liver functional deterioration after liver resection. Laparoscopic group with poorer conditions showed the similar deterioration of liver function and overall survivals to open group.