Fernández-Seara, M.P. (María del Pilar)

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    A bilateral whitish lesion on the mucosa of the cheek
    (Elsevier, 2022) Bronte-Anaut, M. (Mónica); Fernández-Seara, M.P. (María del Pilar); Guarch-Troyas, R. (Rosa); Arredondo-Montero, J. (Javier); Antona, G. (Giuseppa); Ruiz-de-Azúa, Y. (Yerani); Peñafiel-Freire, D.M. (Diego Mauricio)
    An 8-year-old girl with no medical history presented with a bilateral whitish lesion on the mucosa of the cheek, evident since early childhood. There was no relevant family history, and her parents had not presented similar lesions. They reported a progressive growth of the lesion in the last months, for which she had been evaluated by maxillofacial surgery, the lesion being oriented as a frictional keratosis. However, the use of occlusal splint was not associated with any improvement. She was otherwise asymptomatic. Physical examination revealed a bilateral, whitish, well-demarcated cheek mucosal plaque, which partially coincided with the dental occlusion line. The lesion did not detach with scratching (Figure 1). No other alterations were observed in the oral cavity or in the systematic physical examination.
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    Congenital cytomegalovirus infection with brainstem hemorrhage and polymicrogyria: Necropsic and histopathological findings
    (Wiley, 2022) Bronte-Anaut, M. (Mónica); Fernández-Seara, M.P. (María del Pilar); Martin-Calvo, N. (Nerea); Arredondo-Montero, J. (Javier); Caballero, M.C. (M.C.)
    Congenital cytomegalovirus (CMV) infection can cause severe neurological sequelae or even fetal death. We present a 17-year-old pregnant woman with fetal CMV infection, leading to voluntary termination of pregnancy. Fetopsy demonstrated a brainstem hemorrhage and focal polymicrogyria. CMV inclusions were observed in the lung, liver, thyroid, pancreas, kidneys, adrenal, placenta, and central nervous system. Intracranial hemorrhage is a rare finding in the context of congenital CMV infection, with isolated brainstem hemorrhage being an exceptional form of presentation. Polymicrogyria appears to be a more frequent finding, although its actual incidence is unknown. Future studies are needed to determine the causal association.