Briceño, J. (Javier)

Filtering

2008 - 200922020 - 20221

Settings

Author search.filters.isAuthorOfPublication.9d2204aa-c656-4814-9c38-fb7f46b2843d

Search Results

Now showing 1 - 3 of 3
  • Thumbnail Image
    Conservative management of perforated duodenal diverticulum: a case report and review of the literature
    (WJG Press, 2008) Briceño, J. (Javier); Gomez-Alvarez, M. (Manuel); Martinez-Cecilia, D. (David); Valenti, V. (Víctor); Padillo, F.J. (Francisco Javier); Rufian-Peña, S. (Sebastián); Torres-Tordera, E. (Eva); Arjona-Sanchez, A. (Álvaro); Luque-Molina, A. (Antonio); Lopez-Cillero, P. (Pedro)
    Duodenal diverticula are a relatively common condition. They are asymptomatic, unless they become complicated, with perforation being the rarest but most severe complication. Surgical treatment is the most frequently performed approach. We report the case of a patient with a perforated duodenal diverticulum, which was diagnosed early and treated conservatively with antibiotics and percutaneous drainage of secondary retroperitoneal abscesses. We suggest this method could be an acceptable option for the management of similar cases, provided that the patient is in good general condition and without septic signs.
  • Thumbnail Image
    An international retrospective observational study of liver functional deterioration after repeat liver resection for patients with hepatocellular carcinoma
    (2022) Otsuka, Y. (Yuichiro); Buell, J.F. (Joseph F.); Dagher, I. (Ibrahim); Briceño, J. (Javier); Ohmura, Y. (Yoshiaki); Wilson, G.C. (Gregory C.); Wakabayashi, G. (Go); Morise, Z. (Zenichi); Rotellar, F. (Fernando); Seyama, Y. (Yasuji); Okamura, Y. (Yukiyasu); Alzoubi, M. (Mohammad); Belli, A. (Andrea); Ueno, M. (Masaki); Fuks, D. (David); Gayet, B. (Brice); Monden, K. (Kazuteru); Kawamoto, K. (Kazuyuki); Kaizu, T. (Takashi); Troisi, R.I. (Roberto I.); Kumamoto, Y. (Yusuke); Lewin, J. (Joel); Laurent, A. (Alexis); Lin, C.C.W. (Charles Chung-Wei); Cheung, T.T. (Tan To); Yasunaga, M. (Masafumi); Cherqui, D. (Daniel); Edwin, B. (Bjorn); Kato, Y. (Yutaro); Tanabe, M. (Minoru); Ome, Y. (Yusuke); Belli, G. (Giulio); Ciria-Bru, R. (Rubén); Suh, K.S. (Kyung Suk); O’Rourke, N. (Nicholas); Tanaka, S. (Shogo); Chen, K. (KuoHsin); Abu-Hilal, M. (Mohammed); Kaneko, H. (Hironori); Hashida, K. (Kazuki); Yoh, T. (Tomoaki); Shinoda, M. (Masahiro); Ekmekcigil, E. (Ela); Cho, H.D. (Hwui-Dong); Halim, N.A. (Nasser Abdul); Aldrighetti, L. (Luca); Kubo, S. (Shoji); Sadamori, H. (Hiroshi); Gotohda, N. (Naoto); Soubrane, O. (Olivier); Abe, Y. (Yuta); Lo, C.M. (Chung Mau); Geller, D.A. (David A.); Han, H.S. (Ho-Seong); Kanazawa, A. (Akishige); Ogura, T. (Toshiro); Kim, K.H. (Ki Hun); Ratti, F. (Francesca); Nitta, H. (Hiroyuki); Takeda, Y. (Yutaka); Berardi, G. (Giammauro); Sugioka, A. (Atsushi); Uesaka, K. (Katsuhiko)
    Simple Summary For 657 cases of segment or less repeat liver resection with results of plasma albumin and bilirubin levels and platelet counts before and 3 months after surgery, the indicators were compared before and after surgery. There were 268 open repeat after open and 224 cases laparoscopic repeat after laparoscopic liver resection. The background factors and liver functional indicators before and after surgery, and the changes were compared between both groups. Plasma levels of albumin (p = 0.006) and total bilirubin (p = 0.01) were decreased, and ALBI score (p = 0.001) indicated worse liver function after surgery. Though laparoscopic group had poorer performance status and liver function, changes of the values and overall survivals were similar between both groups. Plasma levels of albumin and bilirubin and ALBI score could be the liver functional indicators for liver functional deterioration after liver resection. The laparoscopic group with poorer conditions showed a similar deterioration of liver function and overall survival to the open group. Whether albumin and bilirubin levels, platelet counts, ALBI, and ALPlat scores could be useful for the assessment of permanent liver functional deterioration after repeat liver resection was examined, and the deterioration after laparoscopic procedure was evaluated. For 657 patients with liver resection of segment or less in whom results of plasma albumin and bilirubin levels and platelet counts before and 3 months after surgery could be retrieved, liver functional indicators were compared before and after surgery. There were 268 patients who underwent open repeat after previous open liver resection, and 224 patients who underwent laparoscopic repeat after laparoscopic liver resection. The background factors, liver functional indicators before and after surgery and their changes were compared between both groups. Plasma levels of albumin (p = 0.006) and total bilirubin (p = 0.01) were decreased, and ALBI score (p = 0.001) indicated worse liver function after surgery. Laparoscopic group had poorer preoperative performance status and liver function. Changes of liver functional values before and after surgery and overall survivals were similar between laparoscopic and open groups. Plasma levels of albumin and bilirubin and ALBI score could be the indicators for permanent liver functional deterioration after liver resection. Laparoscopic group with poorer conditions showed the similar deterioration of liver function and overall survivals to open group.
  • No Thumbnail Available
    Alteration of S-nitrosothiol homeostasis and targets for protein S-nitrosation in human hepatocytes
    (Wiley-VCH Verlag Berlin, 2008) Briceño, J. (Javier); Rodriguez-Ariza, A. (Antonio); Corrales, F.J. (Fernando José); Ranchal, I. (Isidora); Muntane, J. (Jordi); Ferrin, G. (Gustavo); Lopez-Sanchez, L.M. (Laura M.); Gonzalez, R. (Raúl); Hidalgo, A.B. (Ana B.); Muñoz-Castañeda, J.R. (Juan R.); Gomez, M.A. (Miguel A.); Lopez-Cillero, P. (Pedro); Mata, M. (Manuel) de la
    The liver is one organ clearly influenced by nitric oxide (NO), and acute and chronic exposure to this substance has been associated with distinct patterns of liver disease. Disruption or deregulation of S-nitrosothiol (SNO) signalling leads to impairment of cellular function and disease, and this study was aimed to identify potential targets for protein S-nitrosation during alteration of SNO homeostasis in human hepatocytes. Cells were treated with S-nitroso-L-cysteine (CSNO), an effective physiological nitrosothiol for delivering NO bioactivity to cells. Treatment with CSNO augmented the levels of S-nitrosoproteins detected both by chemiluminescence and the biotin switch method. CSNO treatment also increased S-nitrosoglutathione reductase (GSNOR) activity that returned SNO content to basal levels. This increased enzymatic activity was related to augmented levels of ADH-5 mRNA, the gene encoding for GSNOR in humans. In addition, the treatment with the SNO also increased cell death. Twenty S-nitrosoproteins were identified in CSNO-treated hepatocytes, including mitochondrial aldehyde dehydrogenase, protein disulphide isomerase, Hsp60, GRP75 and Raf kinase inhibitor protein. The identification in the S-nitrosatable proteome of proteins involved in metabolism, maintenance of cellular homeostasis and signalling points to the relevance of protein S-nitrosation to the physiology and pathophysiology of human hepatocytes.