Kropf, S. (Siegfried)
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- Prospective randomized trial of enoxaparin, pentoxifylline and ursodeoxycholic acid for prevention of radiation-induced liver toxicity(Public Library of Science, 2014) Wust, P. (Peter); Mohnike, K. (Konrad); Hass, P. (Peter); Kropf, S. (Siegfried); Sangro, B. (Bruno); Damn, R. (Robert); Seidensticker, R. (Ricarda); Seidensticker, M. (Max); Gademann, G. (Günther); Pech, M. (Maciej); Ricke, J. (Jeans)The post-therapeutic application of PTX, UDCA and low-dose LMWH significantly reduced the extent and incidence fRILI at 6 weeks after radiotherapy. The development of subsequent fRILI at 12 weeks (4 weeks after cessation of PTX, UDCA and LMWH during weeks 1-8) in the treatment group was comparable to the control group thus supporting the observation that the agents mitigated fRILI.