Giuliante, F. (Felice)

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    Primum Non Nocere in interventional oncology for liver cancer: How to reduce the risk for complications?
    (MDPI AG, 2020) Sharma, R.A. (Ricky A.); Iezzi, R. (Roberto); Giuliante, F. (Felice); Gasbarrini, A. (Antonio); Crocetti, L. (Laura); Goldberg, S. (S.); Manfredi, R. (Riccardo); Colosimo, C. (Cesare); Bilhim, T. (Tiago); Bilbao, J.I. (José I.); Valentini, V. (Vincenzo); Akhan, O. (Okan); Sami, A. (Ahmed); Giuliante, M. (Maurizio); Scalise, P. (Paola)
    : Interventional oncology represents a relatively new clinical discipline based upon minimally invasive therapies applicable to almost every human organ and disease. Over the last several decades, rapidly evolving research developments have introduced a newer generation of treatment devices, reagents, and image-guidance systems to expand the armamentarium of interventional oncology across a wide spectrum of disease sites, offering potential cure, control, or palliative care for many types of cancer patients. Due to the widespread use of locoregional procedures, a comprehensive review of the methodologic and technical considerations to optimize patient selection with the aim of performing a safe procedure is mandatory. This article summarizes the expert discussion and report from the Mediterranean Interventional Oncology Live Congress (MIOLive 2020) held in Rome, Italy, integrating evidence-reported literature and experience-based perceptions as a means for providing guidance on prudent ways to reduce complications. The aim of the paper is to provide an updated guiding tool not only to residents and fellows but also to colleagues approaching locoregional treatments.
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    Robotic versus laparoscopic liver resection for huge (≥10 cm) liver tumors: an international multicenter propensity-score matched cohort study of 799 cases
    (2023) Goh, B.K.P. (Brian K. P.); Park, J.O. (James O.); Sutcliffe, R.P. (Robert P.); Kingham, T.P. (T. Peter); Wakabayashi, G. (Go); Herman, P. (Paulo); D'Hondt, M. (Mathieu); Lee, J.H. (Jae Hoon); Rotellar, F. (Fernando); Chiow, A.K.H. (Adrian K. H.); Cipriani, F. (Federica); Giuliante, F. (Felice); Fuks, D. (David); Aghayan, D.L. (Davit L.); Choi, G. (Gi-Hong); Troisi, R.I. (Roberto I.); Mejía, A. (Alejandro); Cheung, T.T. (Tan To); Di-Benedetto, F. (Fabrizio); Cherqui, D. (Daniel); Tang, C. N. (Chung-Ngai); Edwin, B. (Bjorn); Efanov, M. (Mikhail); Robles-Campos, R. (Ricardo); Scatton, O. (Oliver); Wang, X. (Xiaoying); Chen, K. (KuoHsin); Ferrero, A. (Alessandro); Abu-Hilal, M. (Mohammed); Chong, C.C.N (Charing C. N.); Fondevila, C. (Constantino); Choi, S.H. (Sung Hoon); López-Ben, S. (Santiago); Aldrighetti, L. (Luca); Marino, M.V. (Marco V.); Ruzzenente, A. (Andrea); Sucandy, I. (Iswanto); Han, H.S. (Ho-Seong); Liu, R. (Rong); Pratschke, J. (J.); Syn, N.L. (Nicholas L.); Mazzaferro, V. (Vicenzo); Sugioka, A. (Atsushi); Gastaca, M. (Mikel); Long, T.C.D. (Tran Cong Duy)
    Background: The use of laparoscopic (LLR) and robotic liver resections (RLR) has been safely performed in many institutions for liver tumours. A large scale international multicenter study would provide stronger evidence and insight into application of these techniques for huge liver tumours >_10 cm. Methods: This was a retrospective review of 971 patients who underwent LLR and RLR for huge (>_10 cm) tumors at 42 international centers between 2002-2020. Results: One hundred RLR and 699 LLR which met study criteria were included. The comparison between the 2 approaches for patients with huge tumors were performed using 1:3 propensity-score matching (PSM) (73 vs. 219). Before PSM, LLR was associated with significantly increased frequency of previous abdominal surgery, malignant pathology, liver cirrhosis and increased median blood. After PSM, RLR and LLR was associated with no significant difference in key perioperative outcomes including media operation time (242 vs. 290 min, P=0.286), transfusion rate rate (19.2% vs. 16.9%, P=0.652), median blood loss (200 vs. 300 mL, P=0.694), open conversion rate (8.2% vs. 11.0%, P=0.519), morbidity (28.8% vs. 21.9%, P=0.221), major morbidity (4.1% vs. 9.6%, P=0.152), mortality and postoperative length of stay (6 vs. 6 days, P=0.435). Conclusions: RLR and LLR can be performed safely for selected patients with huge liver tumours with excellent outcomes. There was no significant difference in perioperative outcomes after RLR or LLR.